Lisdexamfetamine: study card

Lisdexamfetamine — CNS stimulant (amphetamine prodrug). Study the mechanism, listed uses and warnings from the US label on one sourced card.

Generic name
Lisdexamfetamine
Class
CNS stimulant (amphetamine prodrug)
Mechanism
Prodrug of dextroamphetamine, a non-catecholamine sympathomimetic amine with CNS stimulant activity.
Used for
ADHD in adults and children aged 6 or older; Moderate-to-severe binge-eating disorder in adults
Common side effects
Decreased appetite; Insomnia; Dry mouth; Irritability; Upper abdominal pain
Boxed warning
High potential for abuse and misuse, which can lead to substance use disorder, overdose and death.
Warnings
Serious cardiac disease; Increased blood pressure and heart rate; Growth suppression in children; Not indicated for weight loss; safety and effectiveness for obesity have not been established
Interactions
MAOIs (contraindicated); Urinary acidifying / alkalinizing agents

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

Read the source label ↗

Label date: 20260707 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.

Pronunciation

Lisdexamfetamine: lis-dex-am-FET-a-meen

Pronunciation is shown for the US English generic name.

Body system

Psychiatry · 30 Drug cards

Compare with related cards

Methylphenidate

Same body system: Psychiatry

Mechanism: Blocks reuptake of norepinephrine and dopamine into presynaptic neurons and increases their release; therapeutic mode in ADHD unknown.

On both cards: Common side effects — Decreased appetite; Insomnia; Dry mouth

Only on the Methylphenidate card: Used for — ADHD (ages 6 to 65) · Common side effects — Headache; Upper abdominal pain (pediatric) · Warnings — Serious cardiac disease; increased BP and heart rate; Psychiatric reactions (mania, psychosis); Pediatric growth suppression; priapism · Interactions — MAO inhibitors (hypertensive crisis); Antihypertensive drugs; Halogenated anesthetics

Atomoxetine

Same body system: Psychiatry

Mechanism: Thought to act by selective inhibition of the presynaptic norepinephrine transporter.

On both cards: Common side effects — Decreased appetite; Dry mouth · Interactions — MAOIs (contraindicated)

Only on the Atomoxetine card: Used for — ADHD (children 6+ and adults) · Common side effects — Nausea; Fatigue / somnolence; Constipation · Warnings — Severe liver injury; Serious cardiovascular reactions; raised BP and heart rate; Psychotic or manic symptoms · Interactions — Strong CYP2D6 inhibitors; Albuterol / other beta2 agonists

Bupropion

Same body system: Psychiatry

Mechanism: Relatively weak inhibitor of neuronal norepinephrine and dopamine reuptake; does not inhibit serotonin reuptake or monoamine oxidase.

On both cards: Common side effects — Insomnia; Dry mouth

Only on the Bupropion card: Used for — Major depressive disorder in adults · Common side effects — Headache; Nausea; Dizziness · Warnings — Seizure risk (dose-related); Neuropsychiatric events in smoking cessation; Hypertension · Interactions — CYP2B6 inducers; CYP2D6 substrates (e.g. metoprolol); MAOIs

An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.

Boxed warnings on related cards

Other cards with a boxed warning in this body system (Psychiatry): Sertraline, Escitalopram, Bupropion, Fluoxetine, Trazodone, Amphetamine / Dextroamphetamine, Duloxetine, Alprazolam, Citalopram, Venlafaxine, Zolpidem, Methylphenidate (+14)