Citalopram — Selective serotonin reuptake inhibitor (SSRI). Study the mechanism, listed uses and warnings from the US label on one sourced card.
Generic name
Citalopram
Class
Selective serotonin reuptake inhibitor (SSRI)
Mechanism
Presumed to potentiate CNS serotonergic activity by inhibiting neuronal reuptake of serotonin (5-HT).
Used for
Major depressive disorder (adults)
Common side effects
Ejaculation disorder (delay); Sexual dysfunction
Boxed warning
Antidepressants increased suicidal thoughts and behaviors in pediatric and young adult patients; not approved in children.
Warnings
QT prolongation / torsade de pointes; Serotonin syndrome; Contraindicated with MAOIs or pimozide
Interactions
MAO inhibitors; Pimozide and other QT-prolonging drugs; CYP2C19 inhibitors
Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.
Label date: 20260904 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Potentiates serotonergic activity in the CNS by inhibiting neuronal reuptake of serotonin (5-HT).
On both cards: Warnings — Serotonin syndrome
Only on the Sertraline card: Used for — Major depressive disorder in adults; Obsessive-compulsive disorder in adults and children aged 6–17 years; Panic disorder, PTSD or social anxiety disorder in adults; Premenstrual dysphoric disorder in adults · Common side effects — Nausea; Diarrhea / loose stool; Tremor; Hyperhidrosis; Ejaculation failure · Warnings — Increased risk of bleeding; Activation of mania / hypomania · Interactions — MAOIs (incl. linezolid, IV methylene blue); Pimozide; Warfarin and other protein-bound drugs
Mechanism: The S-enantiomer of citalopram inhibits neuronal serotonin reuptake. Its antidepressant action is presumed to relate to increased serotonergic activity in the CNS.
On both cards: Warnings — Serotonin syndrome
Only on the Escitalopram card: Used for — Major depressive disorder in adults and children aged 12 years and older; Generalized anxiety disorder in adults · Common side effects — Insomnia; Ejaculation disorder; Nausea; Increased sweating; Fatigue, somnolence · Warnings — Hyponatremia; Increased risk of bleeding · Interactions — MAOIs (incl. linezolid, IV methylene blue); Pimozide; NSAIDs, aspirin, warfarin
Mechanism: Exact mechanism unknown; presumed linked to inhibition of CNS neuronal uptake of serotonin.
On both cards: Warnings — Serotonin syndrome
Only on the Fluoxetine card: Used for — Major depressive disorder in adults and children aged 8 years and older; Obsessive-compulsive disorder in adults and children aged 7 years and older; Binge-eating and vomiting in adults with moderate to severe bulimia nervosa; Panic disorder in adults · Common side effects — Nausea; Insomnia; Anxiety; Somnolence; Diarrhea · Warnings — Allergic reactions and rash; Suicidal thoughts in young patients · Interactions — MAOIs; CYP2D6 substrates (potent CYP2D6 inhibitor); Tricyclic antidepressants
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.
Boxed warnings on related cards
Sertraline: Antidepressants increased the risk of suicidal thoughts and behaviors in pediatric and young adult patients.
Escitalopram: Antidepressants increased the risk of suicidal thoughts and behaviors in pediatric and young adult patients.
Fluoxetine: Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents and young adults.
Paroxetine: Antidepressants increased suicidal thoughts and behaviors in pediatric and young adult patients.
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