Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.
Label date: 20260827 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Exact mechanism unknown; believed to potentiate serotonergic and noradrenergic activity in the CNS.
On both cards: Used for — Major depressive disorder in adults · Common side effects — Dry mouth; Nausea · Interactions — MAOIs
Only on the Duloxetine card: Used for — Generalized anxiety disorder in adults and children aged 7 years and older; Diabetic peripheral neuropathic pain in adults; Fibromyalgia in adults and adolescents aged 13 years and older; Chronic musculoskeletal pain in adults · Common side effects — Somnolence; Constipation; Hyperhidrosis · Warnings — Hepatotoxicity; Orthostatic hypotension, falls, syncope; Serotonin syndrome · Interactions — Potent CYP1A2 inhibitors; Potent CYP2D6 inhibitors
Mechanism: Exact mechanism unknown; presumed linked to inhibition of CNS neuronal uptake of serotonin.
On both cards: Common side effects — Nausea; Insomnia · Interactions — MAOIs
Only on the Fluoxetine card: Used for — Major depressive disorder in adults and children aged 8 years and older; Obsessive-compulsive disorder in adults and children aged 7 years and older; Binge-eating and vomiting in adults with moderate to severe bulimia nervosa; Panic disorder in adults · Common side effects — Anxiety; Somnolence; Diarrhea · Warnings — Serotonin syndrome; Allergic reactions and rash; Suicidal thoughts in young patients · Interactions — CYP2D6 substrates (potent CYP2D6 inhibitor); Tricyclic antidepressants
Mechanism: Mechanism is unknown. Preclinical studies show high 5-HT1A receptor affinity; buspirone also has moderate D2 affinity, no significant benzodiazepine-receptor affinity and no effect on GABA binding in the tested preclinical models.
On both cards: Common side effects — Headache; Nausea; Dizziness
Only on the Buspirone card: Used for — Anxiety disorders; Short-term relief of anxiety symptoms · Common side effects — Nervousness; Lightheadedness · Warnings — Contraindicated with MAOIs (serotonin syndrome); Hypersensitivity to buspirone · Interactions — MAO inhibitors; Linezolid / IV methylene blue; CYP3A4 inhibitors and inducers
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.