Short-term studies showed increased suicidal ideation in pediatric ADHD patients aged 6 or older. Monitor closely for suicidal thoughts or behavior, clinical worsening and unusual behavior, especially during the initial months and after dose changes.
Warnings
Severe liver injury; Serious cardiovascular reactions; raised BP and heart rate; Psychotic or manic symptoms
Interactions
MAOIs (contraindicated); Strong CYP2D6 inhibitors; Albuterol / other beta2 agonists
Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.
Label date: 20260904 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Exact mechanism unknown; believed to potentiate serotonergic and noradrenergic activity in the CNS.
On both cards: Common side effects — Nausea; Dry mouth; Constipation
Only on the Duloxetine card: Used for — Major depressive disorder in adults; Generalized anxiety disorder in adults and children aged 7 years and older; Diabetic peripheral neuropathic pain in adults; Fibromyalgia in adults and adolescents aged 13 years and older; Chronic musculoskeletal pain in adults · Common side effects — Somnolence; Hyperhidrosis · Warnings — Hepatotoxicity; Orthostatic hypotension, falls, syncope; Serotonin syndrome · Interactions — Potent CYP1A2 inhibitors; Potent CYP2D6 inhibitors; MAOIs
Mechanism: Presumed to potentiate CNS serotonergic activity by inhibiting neuronal reuptake of serotonin (5-HT).
On both cards: Common side effects — Nausea; Dry mouth · Interactions — MAOIs (contraindicated)
Only on the Paroxetine card: Used for — Major depressive disorder in adults; Obsessive-compulsive disorder and panic disorder in adults; Social anxiety disorder and generalized anxiety disorder in adults; Posttraumatic stress disorder in adults · Common side effects — Somnolence; Abnormal ejaculation; Sweating · Warnings — Serotonin syndrome; Embryofetal toxicity; Increased risk of bleeding · Interactions — Thioridazine / pimozide (contraindicated); Anticoagulants / NSAIDs
Mechanism: May act through partial agonism at D2 and 5-HT1A receptors and antagonism at 5-HT2A receptors.
On both cards: Common side effects — Nausea; Constipation · Interactions — Strong CYP2D6 inhibitors
Only on the Aripiprazole card: Used for — Schizophrenia in adults and adolescents aged 13–17; Acute bipolar I manic or mixed episodes in adults and patients aged 10–17, alone or with lithium or valproate; Adjunct to antidepressants for major depressive disorder in adults; Irritability associated with autistic disorder at ages 6–17; Tourette disorder at ages 6–18 · Common side effects — Akathisia; Headache; Insomnia · Warnings — Neuroleptic malignant syndrome; Tardive dyskinesia; Pathological gambling / compulsive behaviors · Interactions — Strong CYP3A4 inhibitors; Strong CYP3A4 inducers
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.
Capsera