Amphetamine / Dextroamphetamine: study card

Amphetamine / Dextroamphetamine — CNS stimulant (mixed amphetamine salts). Study the mechanism, listed uses and warnings from the US label on one sourced card.

Generic name
Amphetamine / Dextroamphetamine
Class
CNS stimulant (mixed amphetamine salts)
Mechanism
Non-catecholamine sympathomimetic amines with CNS stimulant activity; mode of therapeutic action in ADHD is not known.
Used for
ADHD in adults and children aged 6 or older, for the cited extended-release capsules
Common side effects
Loss of appetite; Insomnia; Abdominal pain; Emotional lability; Nervousness
Boxed warning
High potential for abuse and misuse, which can lead to substance use disorder, including addiction.
Warnings
Serious cardiac disease risks; Increased blood pressure and heart rate; Psychiatric adverse reactions
Interactions
MAOIs; Alkalinizing agents; Acidifying agents

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

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Label date: 20260618 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.

Pronunciation

Amphetamine: am-FET-a-meen · Dextroamphetamine: dex-troe-am-FET-a-meen

Pronunciation is shown for the US English generic name.

Body system

Psychiatry · 30 Drug cards

Compare with related cards

Bupropion

Same body system: Psychiatry

Mechanism: Relatively weak inhibitor of neuronal norepinephrine and dopamine reuptake; does not inhibit serotonin reuptake or monoamine oxidase.

On both cards: Common side effects — Insomnia · Interactions — MAOIs

Only on the Bupropion card: Used for — Major depressive disorder in adults · Common side effects — Headache; Dry mouth; Nausea; Dizziness · Warnings — Seizure risk (dose-related); Neuropsychiatric events in smoking cessation; Hypertension · Interactions — CYP2B6 inducers; CYP2D6 substrates (e.g. metoprolol)

Fluoxetine

Same body system: Psychiatry

Mechanism: Exact mechanism unknown; presumed linked to inhibition of CNS neuronal uptake of serotonin.

On both cards: Common side effects — Insomnia · Interactions — MAOIs

Only on the Fluoxetine card: Used for — Major depressive disorder in adults and children aged 8 years and older; Obsessive-compulsive disorder in adults and children aged 7 years and older; Binge-eating and vomiting in adults with moderate to severe bulimia nervosa; Panic disorder in adults · Common side effects — Nausea; Anxiety; Somnolence; Diarrhea · Warnings — Serotonin syndrome; Allergic reactions and rash; Suicidal thoughts in young patients · Interactions — CYP2D6 substrates (potent CYP2D6 inhibitor); Tricyclic antidepressants

Lisdexamfetamine

Same body system: Psychiatry

Mechanism: Prodrug of dextroamphetamine, a non-catecholamine sympathomimetic amine with CNS stimulant activity.

On both cards: Common side effects — Insomnia · Warnings — Increased blood pressure and heart rate

Only on the Lisdexamfetamine card: Used for — ADHD in adults and children aged 6 or older; Moderate-to-severe binge-eating disorder in adults · Common side effects — Decreased appetite; Dry mouth; Irritability; Upper abdominal pain · Warnings — Serious cardiac disease; Growth suppression in children; Not indicated for weight loss; safety and effectiveness for obesity have not been established · Interactions — MAOIs (contraindicated); Urinary acidifying / alkalinizing agents

An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.

Boxed warnings on related cards

Other cards with a boxed warning in this body system (Psychiatry): Sertraline, Escitalopram, Bupropion, Fluoxetine, Trazodone, Duloxetine, Alprazolam, Citalopram, Venlafaxine, Zolpidem, Methylphenidate, Lorazepam (+14)