Escitalopram: brand names and study card

Escitalopram — Selective serotonin reuptake inhibitor (SSRI). Study the mechanism, listed uses and warnings from the US label on one sourced card.

Generic name
Escitalopram
Brands
Lexapro
Class
Selective serotonin reuptake inhibitor (SSRI)
Mechanism
The S-enantiomer of citalopram inhibits neuronal serotonin reuptake. Its antidepressant action is presumed to relate to increased serotonergic activity in the CNS.
Used for
Major depressive disorder in adults and children aged 12 years and older; Generalized anxiety disorder in adults
Common side effects
Insomnia; Ejaculation disorder; Nausea; Increased sweating; Fatigue, somnolence
Boxed warning
Antidepressants increased the risk of suicidal thoughts and behaviors in pediatric and young adult patients.
Warnings
Serotonin syndrome; Hyponatremia; Increased risk of bleeding
Interactions
MAOIs (incl. linezolid, IV methylene blue); Pimozide; NSAIDs, aspirin, warfarin

Drug class families: Selective serotonin reuptake inhibitors

Read the source label ↗

Label date: 20260720 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.

Pronunciation

Escitalopram: es-sye-TAL-oh-pram

Pronunciation is shown for the US English generic name.

Other drugs in the same class

Selective serotonin reuptake inhibitors: Fluoxetine, Citalopram, Paroxetine, Sertraline

Body system

Psychiatry · 30 Drug cards

Compare with related cards

Sertraline

Same class family: Selective serotonin reuptake inhibitors

Mechanism: Potentiates serotonergic activity in the CNS by inhibiting neuronal reuptake of serotonin (5-HT).

On both cards: Common side effects — Nausea · Warnings — Serotonin syndrome; Increased risk of bleeding · Interactions — MAOIs (incl. linezolid, IV methylene blue); Pimozide

Only on the Sertraline card: Used for — Major depressive disorder in adults; Obsessive-compulsive disorder in adults and children aged 6–17 years; Panic disorder, PTSD or social anxiety disorder in adults; Premenstrual dysphoric disorder in adults · Common side effects — Diarrhea / loose stool; Tremor; Hyperhidrosis; Ejaculation failure · Warnings — Activation of mania / hypomania · Interactions — Warfarin and other protein-bound drugs

Fluoxetine

Same class family: Selective serotonin reuptake inhibitors

Mechanism: Exact mechanism unknown; presumed linked to inhibition of CNS neuronal uptake of serotonin.

On both cards: Common side effects — Insomnia; Nausea · Warnings — Serotonin syndrome

Only on the Fluoxetine card: Used for — Major depressive disorder in adults and children aged 8 years and older; Obsessive-compulsive disorder in adults and children aged 7 years and older; Binge-eating and vomiting in adults with moderate to severe bulimia nervosa; Panic disorder in adults · Common side effects — Anxiety; Somnolence; Diarrhea · Warnings — Allergic reactions and rash; Suicidal thoughts in young patients · Interactions — MAOIs; CYP2D6 substrates (potent CYP2D6 inhibitor); Tricyclic antidepressants

Paroxetine

Same class family: Selective serotonin reuptake inhibitors

Mechanism: Presumed to potentiate CNS serotonergic activity by inhibiting neuronal reuptake of serotonin (5-HT).

On both cards: Common side effects — Nausea · Warnings — Serotonin syndrome; Increased risk of bleeding

Only on the Paroxetine card: Used for — Major depressive disorder in adults; Obsessive-compulsive disorder and panic disorder in adults; Social anxiety disorder and generalized anxiety disorder in adults; Posttraumatic stress disorder in adults · Common side effects — Somnolence; Abnormal ejaculation; Dry mouth; Sweating · Warnings — Embryofetal toxicity · Interactions — MAOIs (contraindicated); Thioridazine / pimozide (contraindicated); Anticoagulants / NSAIDs

An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.

Boxed warnings on related cards

Same boxed-warning wording on: Sertraline

Fluoxetine: Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents and young adults.

Citalopram: Antidepressants increased suicidal thoughts and behaviors in pediatric and young adult patients; not approved in children.

Paroxetine: Antidepressants increased suicidal thoughts and behaviors in pediatric and young adult patients.