Sertraline — Selective serotonin reuptake inhibitor (SSRI). Study the mechanism, listed uses and warnings from the US label on one sourced card.
Generic name
Sertraline
Class
Selective serotonin reuptake inhibitor (SSRI)
Mechanism
Potentiates serotonergic activity in the CNS by inhibiting neuronal reuptake of serotonin (5-HT).
Used for
Major depressive disorder in adults; Obsessive-compulsive disorder in adults and children aged 6–17 years; Panic disorder, PTSD or social anxiety disorder in adults; Premenstrual dysphoric disorder in adults
Antidepressants increased the risk of suicidal thoughts and behaviors in pediatric and young adult patients.
Warnings
Serotonin syndrome; Increased risk of bleeding; Activation of mania / hypomania
Interactions
MAOIs (incl. linezolid, IV methylene blue); Pimozide; Warfarin and other protein-bound drugs
Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.
Label date: 20260828 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: The S-enantiomer of citalopram inhibits neuronal serotonin reuptake. Its antidepressant action is presumed to relate to increased serotonergic activity in the CNS.
On both cards: Common side effects — Nausea · Warnings — Serotonin syndrome; Increased risk of bleeding · Interactions — MAOIs (incl. linezolid, IV methylene blue); Pimozide
Only on the Escitalopram card: Used for — Major depressive disorder in adults and children aged 12 years and older; Generalized anxiety disorder in adults · Common side effects — Insomnia; Ejaculation disorder; Increased sweating; Fatigue, somnolence · Warnings — Hyponatremia · Interactions — NSAIDs, aspirin, warfarin
Mechanism: Presumed to potentiate CNS serotonergic activity by inhibiting neuronal reuptake of serotonin (5-HT).
On both cards: Used for — Major depressive disorder in adults · Common side effects — Nausea · Warnings — Serotonin syndrome; Increased risk of bleeding
Only on the Paroxetine card: Used for — Obsessive-compulsive disorder and panic disorder in adults; Social anxiety disorder and generalized anxiety disorder in adults; Posttraumatic stress disorder in adults · Common side effects — Somnolence; Abnormal ejaculation; Dry mouth; Sweating · Warnings — Embryofetal toxicity · Interactions — MAOIs (contraindicated); Thioridazine / pimozide (contraindicated); Anticoagulants / NSAIDs
Mechanism: Exact mechanism unknown; presumed linked to inhibition of CNS neuronal uptake of serotonin.
On both cards: Common side effects — Nausea · Warnings — Serotonin syndrome
Only on the Fluoxetine card: Used for — Major depressive disorder in adults and children aged 8 years and older; Obsessive-compulsive disorder in adults and children aged 7 years and older; Binge-eating and vomiting in adults with moderate to severe bulimia nervosa; Panic disorder in adults · Common side effects — Insomnia; Anxiety; Somnolence; Diarrhea · Warnings — Allergic reactions and rash; Suicidal thoughts in young patients · Interactions — MAOIs; CYP2D6 substrates (potent CYP2D6 inhibitor); Tricyclic antidepressants
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.
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