With opioids: profound sedation, respiratory depression, coma, death; abuse, addiction, dependence and withdrawal risks.
Warnings
Strong CYP3A inhibitors are contraindicated except ritonavir, which requires the source-specific dosing precautions; Impaired driving / CNS depression; Neonatal sedation and withdrawal
Interactions
Opioids; Other CNS depressants; CYP3A inhibitors and inducers
Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.
Label date: 20260827 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Precise mechanism unknown; believed to enhance activity of GABA, the major inhibitory CNS neurotransmitter.
On both cards: Used for — Panic disorder with or without agoraphobia in adults · Interactions — Opioids
Only on the Clonazepam card: Used for — Lennox-Gastaut syndrome, akinetic seizures and myoclonic seizures, alone or as adjunctive treatment; Absence seizures unresponsive to succinimides · Common side effects — Drowsiness; Ataxia; Behavior problems · Warnings — Contraindicated in significant liver disease; Contraindicated in acute narrow-angle glaucoma; Benzodiazepine hypersensitivity · Interactions — Phenytoin; CNS depressants
Mechanism: Binds the benzodiazepine site of GABA-A receptors in the brain, enhancing GABA-mediated synaptic inhibition.
On both cards: Warnings — Neonatal sedation and withdrawal · Interactions — Opioids
Only on the Lorazepam card: Used for — Anxiety disorders in adults already receiving stable, evenly divided three-times-daily lorazepam tablets, when converted to the selected LOREEV XR formulation · Common side effects — Sedation; Dizziness; Weakness; Unsteadiness · Warnings — Contraindicated in acute narrow-angle glaucoma; CNS depression · Interactions — Alcohol / CNS depressants; UGT inhibitors
Mechanism: A benzodiazepine that interacts at GABA-A sites; most clinical effects are thought to result from facilitation of the inhibitory neurotransmitter GABA.
On both cards: Interactions — Opioids
Only on the Diazepam card: Used for — Anxiety disorders; Acute alcohol withdrawal; Skeletal muscle spasm (adjunct) · Common side effects — Drowsiness; Fatigue; Muscle weakness; Ataxia · Warnings — Contraindicated in myasthenia gravis and sleep apnea; Acute narrow-angle glaucoma; Severe respiratory or hepatic insufficiency · Interactions — Alcohol and other CNS depressants
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.
Capsera