Aripiprazole — Atypical antipsychotic (D2 partial agonist). Study the mechanism, listed uses and warnings from the US label on one sourced card.
Generic name
Aripiprazole
Class
Atypical antipsychotic (D2 partial agonist)
Mechanism
May act through partial agonism at D2 and 5-HT1A receptors and antagonism at 5-HT2A receptors.
Used for
Schizophrenia in adults and adolescents aged 13–17; Acute bipolar I manic or mixed episodes in adults and patients aged 10–17, alone or with lithium or valproate; Adjunct to antidepressants for major depressive disorder in adults; Irritability associated with autistic disorder at ages 6–17; Tourette disorder at ages 6–18
Increased mortality in elderly patients with dementia-related psychosis; aripiprazole is not approved for that use. Antidepressants increase suicidal thoughts and behaviors in children, adolescents and young adults; monitor for worsening or emerging suicidality.
Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.
Label date: 20260903 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Relatively weak inhibitor of neuronal norepinephrine and dopamine reuptake; does not inhibit serotonin reuptake or monoamine oxidase.
On both cards: Common side effects — Nausea; Headache; Insomnia
Only on the Bupropion card: Used for — Major depressive disorder in adults · Common side effects — Dry mouth; Dizziness · Warnings — Seizure risk (dose-related); Neuropsychiatric events in smoking cessation; Hypertension · Interactions — CYP2B6 inducers; CYP2D6 substrates (e.g. metoprolol); MAOIs
Mechanism: Thought to act by selective inhibition of the presynaptic norepinephrine transporter.
On both cards: Common side effects — Nausea; Constipation · Interactions — Strong CYP2D6 inhibitors
Only on the Atomoxetine card: Used for — ADHD (children 6+ and adults) · Common side effects — Decreased appetite; Fatigue / somnolence; Dry mouth · Warnings — Severe liver injury; Serious cardiovascular reactions; raised BP and heart rate; Psychotic or manic symptoms · Interactions — MAOIs (contraindicated); Albuterol / other beta2 agonists
Mechanism: Mechanism is unclear; activity in schizophrenia may involve combined dopamine D2 and serotonin 5-HT2 receptor antagonism.
On both cards: Common side effects — Akathisia · Warnings — Neuroleptic malignant syndrome; Tardive dyskinesia
Only on the Risperidone card: Used for — Schizophrenia in adults and adolescents aged 13–17 years; Acute manic or mixed episodes of bipolar I disorder: monotherapy in adults and patients aged 10–17 years, or adjunct to lithium or valproate in adults; Irritability associated with autistic disorder in patients aged 5–17 years · Common side effects — Parkinsonism; Sedation; Increased weight; Dizziness · Warnings — Metabolic changes · Interactions — Carbamazepine / enzyme inducers; Fluoxetine / paroxetine (CYP2D6 inhibitors)
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.
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