Quetiapine — Atypical antipsychotic. Study the mechanism, listed uses and warnings from the US label on one sourced card.
Generic name
Quetiapine
Class
Atypical antipsychotic
Mechanism
Mechanism unclear; efficacy may be mediated by combined dopamine D2 and serotonin 5-HT2 receptor antagonism.
Used for
Schizophrenia in adults and adolescents aged 13 years and older; Acute bipolar I mania as monotherapy in adults and children aged 10 years and older, or as adjunct to lithium/divalproex in adults; Acute bipolar depressive episodes as monotherapy in adults
Common side effects
Somnolence; Dry mouth; Dizziness; Constipation; Weight gain
Boxed warning
Antipsychotic treatment increases mortality in older adults with dementia-related psychosis; quetiapine is not approved for that use. The boxed warning also describes increased suicidal thoughts/behavior in children, adolescents and young adults in short-term antidepressant studies and calls for monitoring.
Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.
Label date: 20260817 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Mechanism is unclear; efficacy in schizophrenia may involve combined dopamine and serotonin 5-HT2 antagonism.
On both cards: Common side effects — Somnolence; Dry mouth; Dizziness; Constipation; Weight gain · Warnings — Cerebrovascular events in elderly dementia
Only on the Olanzapine card: Used for — Schizophrenia in adults and adolescents aged 13–17 years; Acute manic or mixed episodes of bipolar I disorder in adults and adolescents aged 13–17 years; maintenance treatment in adults; Adjunct to lithium or valproate for acute manic or mixed episodes of bipolar I disorder in adults · Warnings — Hyperglycemia / diabetes; Dyslipidemia and weight gain · Interactions — Diazepam / alcohol; Carbamazepine; Fluvoxamine
Mechanism: Exact mechanism unknown; believed to potentiate serotonergic and noradrenergic activity in the CNS.
On both cards: Common side effects — Somnolence; Dry mouth; Constipation
Only on the Duloxetine card: Used for — Major depressive disorder in adults; Generalized anxiety disorder in adults and children aged 7 years and older; Diabetic peripheral neuropathic pain in adults; Fibromyalgia in adults and adolescents aged 13 years and older; Chronic musculoskeletal pain in adults · Common side effects — Nausea; Hyperhidrosis · Warnings — Hepatotoxicity; Orthostatic hypotension, falls, syncope; Serotonin syndrome · Interactions — Potent CYP1A2 inhibitors; Potent CYP2D6 inhibitors; MAOIs
Mechanism: May act by antagonizing central presynaptic alpha-2 adrenergic autoreceptors and heteroreceptors, enhancing noradrenergic and serotonergic activity.
On both cards: Common side effects — Somnolence; Dizziness; Weight gain
Only on the Mirtazapine card: Used for — Major depressive disorder in adults · Common side effects — Increased appetite · Warnings — Agranulocytosis; Serotonin syndrome; QT prolongation · Interactions — MAOIs (contraindicated); Other serotonergic drugs
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.
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