Buspirone: study card

Buspirone — Antianxiety agent. Study the mechanism, listed uses and warnings from the US label on one sourced card.

Generic name
Buspirone
Class
Antianxiety agent
Mechanism
Mechanism is unknown. Preclinical studies show high 5-HT1A receptor affinity; buspirone also has moderate D2 affinity, no significant benzodiazepine-receptor affinity and no effect on GABA binding in the tested preclinical models.
Used for
Anxiety disorders; Short-term relief of anxiety symptoms
Common side effects
Dizziness; Nausea; Headache; Nervousness; Lightheadedness
Warnings
Contraindicated with MAOIs (serotonin syndrome); Hypersensitivity to buspirone
Interactions
MAO inhibitors; Linezolid / IV methylene blue; CYP3A4 inhibitors and inducers

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

Read the source label ↗

Label date: 20260731 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.

Pronunciation

Buspirone: byoo-SPYE-rone

Pronunciation is shown for the US English generic name.

Body system

Psychiatry · 30 Drug cards

Compare with related cards

Bupropion

Same body system: Psychiatry

Mechanism: Relatively weak inhibitor of neuronal norepinephrine and dopamine reuptake; does not inhibit serotonin reuptake or monoamine oxidase.

On both cards: Common side effects — Dizziness; Nausea; Headache

Only on the Bupropion card: Used for — Major depressive disorder in adults · Common side effects — Dry mouth; Insomnia · Warnings — Seizure risk (dose-related); Neuropsychiatric events in smoking cessation; Hypertension · Interactions — CYP2B6 inducers; CYP2D6 substrates (e.g. metoprolol); MAOIs

Venlafaxine

Same body system: Psychiatry

Mechanism: Thought to potentiate serotonin and norepinephrine in the CNS by inhibiting their reuptake.

On both cards: Common side effects — Nausea · Interactions — MAO inhibitors

Only on the Venlafaxine card: Used for — Major depressive disorder in adults; Generalized anxiety disorder in adults; Social anxiety disorder in adults; Panic disorder in adults · Common side effects — Somnolence; Dry mouth; Sweating; Abnormal ejaculation · Warnings — Serotonin syndrome; Elevated blood pressure; Discontinuation syndrome · Interactions — Other serotonergic drugs; Antiplatelets / anticoagulants

Aripiprazole

Same body system: Psychiatry

Mechanism: May act through partial agonism at D2 and 5-HT1A receptors and antagonism at 5-HT2A receptors.

On both cards: Common side effects — Nausea; Headache

Only on the Aripiprazole card: Used for — Schizophrenia in adults and adolescents aged 13–17; Acute bipolar I manic or mixed episodes in adults and patients aged 10–17, alone or with lithium or valproate; Adjunct to antidepressants for major depressive disorder in adults; Irritability associated with autistic disorder at ages 6–17; Tourette disorder at ages 6–18 · Common side effects — Akathisia; Insomnia; Constipation · Warnings — Neuroleptic malignant syndrome; Tardive dyskinesia; Pathological gambling / compulsive behaviors · Interactions — Strong CYP2D6 inhibitors; Strong CYP3A4 inhibitors; Strong CYP3A4 inducers

An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.