Meloxicam — Nonsteroidal anti-inflammatory drug (NSAID). Study the mechanism, listed uses and warnings from the US label on one sourced card.
Generic name
Meloxicam
Class
Nonsteroidal anti-inflammatory drug (NSAID)
Mechanism
Inhibits cyclooxygenase (COX-1 and COX-2) and prostaglandin synthesis; analgesic, anti-inflammatory and antipyretic.
Used for
Relief of osteoarthritis signs and symptoms; Relief of rheumatoid arthritis signs and symptoms; Pauciarticular or polyarticular juvenile rheumatoid arthritis in patients weighing at least 60 kg
NSAIDs can cause serious, potentially fatal cardiovascular thrombotic events and GI bleeding, ulceration or perforation. Meloxicam is contraindicated in the coronary artery bypass graft surgery setting.
Warnings
Hepatotoxicity; Heart failure and edema; Renal toxicity
Interactions
Anticoagulants (e.g. warfarin); SSRIs / SNRIs
Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.
Label date: 20260819 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Mechanism is incompletely understood but involves COX-1 and COX-2 inhibition; reduced prostaglandin synthesis may contribute to its peripheral effects.
On both cards: Common side effects — Dyspepsia · Warnings — Hepatotoxicity; Heart failure and edema; Renal toxicity
Only on the Indomethacin card: Used for — Moderate-to-severe rheumatoid arthritis, including acute flares; Moderate-to-severe ankylosing spondylitis; Moderate-to-severe osteoarthritis; Acute painful shoulder caused by bursitis and/or tendinitis · Common side effects — Headache; Dizziness; Nausea · Interactions — Anticoagulants (e.g., warfarin); Aspirin and antiplatelets; SSRIs and SNRIs
Mechanism: Has analgesic, anti-inflammatory and antipyretic effects; its mechanism is believed to involve reduced prostaglandin synthesis, primarily through COX-2 inhibition.
On both cards: Common side effects — Diarrhea; Upper respiratory tract infection; Dyspepsia
Only on the Celecoxib card: Used for — Signs and symptoms of osteoarthritis or rheumatoid arthritis; Juvenile rheumatoid arthritis from age 2 years; ankylosing spondylitis; Acute pain in adults; Primary dysmenorrhea · Common side effects — Abdominal pain; Peripheral edema · Warnings — Sulfonamide allergy; aspirin/NSAID allergy; Hepatotoxicity; renal toxicity; Heart failure, hypertension, fetal toxicity · Interactions — Anticoagulants / antiplatelets; SSRIs / SNRIs (bleeding); Aspirin (analgesic doses)
Mechanism: The mechanism is not completely understood but involves inhibition of COX-1 and COX-2. Diclofenac inhibits prostaglandin synthesis in vitro; reduced peripheral prostaglandins may contribute to its analgesic and anti-inflammatory effects.
On both cards: Warnings — Hepatotoxicity; Heart failure and edema; Renal toxicity
Only on the Diclofenac (topical) card: Used for — Pain of osteoarthritis of the knee · Common side effects — Application site dryness; Exfoliation; Erythema; Pruritus · Interactions — Anticoagulants (warfarin); Drugs interfering with hemostasis (SSRIs)
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.
Boxed warnings on related cards
Ibuprofen: NSAIDs increase risk of serious CV thrombotic events and GI bleeding, ulceration and perforation; not for CABG setting.
Naproxen: NSAIDs raise risk of serious CV thrombotic events (MI, stroke) and GI bleeding, ulceration, perforation; contraindicated in CABG.
Celecoxib: NSAIDs raise risk of serious CV thrombotic events (MI, stroke) and GI bleeding, ulceration, perforation; contraindicated in CABG.
Diclofenac (oral): Increased risk of serious CV thrombotic events (MI, stroke) and GI bleeding, ulceration and perforation.
Capsera