Ketorolac (oral): study card

Ketorolac (oral) — NSAID (short-term analgesic). Study the mechanism, listed uses and warnings from the US label on one sourced card.

Generic name
Ketorolac
Class
NSAID (short-term analgesic)
Mechanism
NSAID analgesic with an incompletely understood mechanism that may involve prostaglandin-synthetase inhibition.
Used for
Continuation after IV/IM ketorolac for moderately severe acute pain requiring opioid-level analgesia in adults; combined IV/IM plus oral treatment must not exceed 5 days
Common side effects
GI ulceration and bleeding; Postoperative bleeding; Acute renal failure
Boxed warning
Total oral plus IV/IM use must not exceed 5 days; high risk of GI bleeding, renal and CV events.
Warnings
Contraindicated with peptic ulcer or GI bleeding; Not for pediatric or chronic pain; Aspirin/NSAID-induced asthma
Interactions
Warfarin and heparin; Salicylates

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

Drug class families: Nonsteroidal anti-inflammatory drugs

Read the source label ↗

Label date: 20260817 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.

Pronunciation

Ketorolac: KEE-toe-ROLE-ak

Pronunciation is shown for the US English generic name.

Other drugs in the same class

Nonsteroidal anti-inflammatory drugs: Ketorolac (ophthalmic), Indomethacin, Nabumetone, Etodolac, Ibuprofen, Meloxicam, Aspirin, Naproxen

Body system

Pain · 16 Drug cards

Compare with related cards

Ibuprofen

Same class family: Nonsteroidal anti-inflammatory drugs

Mechanism: Has analgesic, antipyretic and anti-inflammatory effects. The selected label says the mechanism is not fully understood and may involve inhibition of prostaglandin synthesis.

Only on the Ibuprofen card: Used for — Rheumatoid arthritis and osteoarthritis; Mild to moderate pain; Primary dysmenorrhea · Common side effects — Nausea; Heartburn; Dizziness; Rash · Warnings — Around 20 weeks of pregnancy onward: fetal kidney injury and low amniotic fluid; restrict use between about 20 and 30 weeks; Avoid at about 30 weeks of pregnancy onward because the fetal ductus arteriosus can close prematurely; Hypertension and heart failure; Renal toxicity · Interactions — ACE inhibitors; Low-dose aspirin (reduced effect); Anticoagulants

Meloxicam

Same class family: Nonsteroidal anti-inflammatory drugs

Mechanism: Inhibits cyclooxygenase (COX-1 and COX-2) and prostaglandin synthesis; analgesic, anti-inflammatory and antipyretic.

Only on the Meloxicam card: Used for — Relief of osteoarthritis signs and symptoms; Relief of rheumatoid arthritis signs and symptoms; Pauciarticular or polyarticular juvenile rheumatoid arthritis in patients weighing at least 60 kg · Common side effects — Diarrhea; Upper respiratory tract infection; Dyspepsia; Influenza-like symptoms · Warnings — Hepatotoxicity; Heart failure and edema; Renal toxicity · Interactions — Anticoagulants (e.g. warfarin); SSRIs / SNRIs

Aspirin

Same class family: Nonsteroidal anti-inflammatory drugs

Mechanism: Aspirin inhibits prostaglandin synthesis and platelet aggregation through cyclooxygenase acetylation; its irreversible platelet COX-1 inhibition reduces thromboxane A2 formation.

Only on the Aspirin card: Used for — Minor aches and pains; Headache and toothache; Menstrual and arthritis pain · Common side effects — Stomach bleeding; Ringing in the ears; Allergic reaction (hives, asthma) · Warnings — Reye's syndrome risk: children and teenagers with or recovering from chickenpox or flu-like symptoms should not use this product; Severe stomach bleeding risk; Do not use at 20 weeks of pregnancy or later unless specifically directed by a doctor · Interactions — Anticoagulants (bleeding); Diuretics; Diabetes, gout and arthritis drugs

An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.

Boxed warnings on related cards

Ibuprofen: NSAIDs increase risk of serious CV thrombotic events and GI bleeding, ulceration and perforation; not for CABG setting.

Meloxicam: NSAIDs can cause serious, potentially fatal cardiovascular thrombotic events and GI bleeding, ulceration or perforation. Meloxicam is contraindicated in the coronary artery bypass graft surgery setting.

Naproxen: NSAIDs raise risk of serious CV thrombotic events (MI, stroke) and GI bleeding, ulceration, perforation; contraindicated in CABG.

Celecoxib: NSAIDs raise risk of serious CV thrombotic events (MI, stroke) and GI bleeding, ulceration, perforation; contraindicated in CABG.