Celecoxib: study card

Celecoxib — NSAID, selective COX-2 inhibitor. Study the mechanism, listed uses and warnings from the US label on one sourced card.

Generic name
Celecoxib
Class
NSAID, selective COX-2 inhibitor
Mechanism
Has analgesic, anti-inflammatory and antipyretic effects; its mechanism is believed to involve reduced prostaglandin synthesis, primarily through COX-2 inhibition.
Used for
Signs and symptoms of osteoarthritis or rheumatoid arthritis; Juvenile rheumatoid arthritis from age 2 years; ankylosing spondylitis; Acute pain in adults; Primary dysmenorrhea
Common side effects
Abdominal pain; Diarrhea; Dyspepsia; Peripheral edema; Upper respiratory tract infection
Boxed warning
NSAIDs raise risk of serious CV thrombotic events (MI, stroke) and GI bleeding, ulceration, perforation; contraindicated in CABG.
Warnings
Sulfonamide allergy; aspirin/NSAID allergy; Hepatotoxicity; renal toxicity; Heart failure, hypertension, fetal toxicity
Interactions
Anticoagulants / antiplatelets; SSRIs / SNRIs (bleeding); Aspirin (analgesic doses)

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

Drug class families: Nonsteroidal anti-inflammatory drugs

Read the source label ↗

Label date: 20260902 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.

Pronunciation

Celecoxib: sel-e-KOX-ib

Pronunciation is shown for the US English generic name.

Other drugs in the same class

Nonsteroidal anti-inflammatory drugs: Diclofenac (oral), Diclofenac (topical), Ketorolac (oral), Ketorolac (ophthalmic), Indomethacin, Nabumetone, Etodolac, Ibuprofen

Body system

Pain · 16 Drug cards

Compare with related cards

Naproxen

Same class family: Nonsteroidal anti-inflammatory drugs

Mechanism: Has analgesic, anti-inflammatory and antipyretic effects. The mechanism is not completely understood but involves COX-1 and COX-2 inhibition; reduced prostaglandin production may contribute.

On both cards: Used for — Primary dysmenorrhea · Common side effects — Abdominal pain; Dyspepsia · Interactions — Anticoagulants / antiplatelets; SSRIs / SNRIs (bleeding)

Only on the Naproxen card: Used for — Rheumatoid arthritis, osteoarthritis, AS; Tendonitis, bursitis, acute gout; Pain · Common side effects — Nausea; Headache; Edema · Warnings — Aspirin-sensitive asthma / NSAID allergy; Renal toxicity and hyperkalemia; Hepatotoxicity, heart failure, fetal toxicity · Interactions — Low-dose aspirin

Etodolac

Same class family: Nonsteroidal anti-inflammatory drugs

Mechanism: Shows anti-inflammatory, analgesic and antipyretic activity in animal models. Its mechanism is not completely understood and may involve prostaglandin-synthetase inhibition.

On both cards: Used for — Acute pain in adults · Common side effects — Abdominal pain; Diarrhea; Dyspepsia

Only on the Etodolac card: Used for — Signs and symptoms of osteoarthritis or rheumatoid arthritis in adults · Common side effects — Nausea; Dizziness · Warnings — Asthma or allergy after aspirin/other NSAIDs; New or worsening hypertension, heart failure; Hepatic reactions, elevated liver tests · Interactions — Warfarin (synergistic GI bleeding); ACE inhibitors, thiazide and loop diuretics; Lithium, methotrexate, cyclosporine, digoxin

Meloxicam

Same class family: Nonsteroidal anti-inflammatory drugs

Mechanism: Inhibits cyclooxygenase (COX-1 and COX-2) and prostaglandin synthesis; analgesic, anti-inflammatory and antipyretic.

On both cards: Common side effects — Diarrhea; Dyspepsia; Upper respiratory tract infection

Only on the Meloxicam card: Used for — Relief of osteoarthritis signs and symptoms; Relief of rheumatoid arthritis signs and symptoms; Pauciarticular or polyarticular juvenile rheumatoid arthritis in patients weighing at least 60 kg · Common side effects — Influenza-like symptoms · Warnings — Hepatotoxicity; Heart failure and edema; Renal toxicity · Interactions — Anticoagulants (e.g. warfarin); SSRIs / SNRIs

An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.

Boxed warnings on related cards

Same boxed-warning wording on: Naproxen

Ibuprofen: NSAIDs increase risk of serious CV thrombotic events and GI bleeding, ulceration and perforation; not for CABG setting.

Meloxicam: NSAIDs can cause serious, potentially fatal cardiovascular thrombotic events and GI bleeding, ulceration or perforation. Meloxicam is contraindicated in the coronary artery bypass graft surgery setting.

Diclofenac (oral): Increased risk of serious CV thrombotic events (MI, stroke) and GI bleeding, ulceration and perforation.

Diclofenac (topical): NSAIDs increase the risk of potentially fatal cardiovascular thrombotic events (including MI and stroke) and gastrointestinal bleeding, ulceration and perforation. This topical solution is contraindicated in the setting of CABG surgery.