CapseraACE inhibitors
Compare the named medicines in this source-linked class directory.
Membership describes a named action or a component of a combination. A medicine may appear in several families. Medicines in one family are not automatically interchangeable; this is a study directory, not a prescribing guide.
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Combination: membership refers to the relevant component.
Combination: membership refers to the relevant component.
Generic names and pronunciation
Shared name ending: -pril · Lisinopril, Benazepril, Enalapril, Ramipril
| Lisinopril · ly-SIN-oh-pril |
| Hydrochlorothiazide · hye-droe-klor-oh-THYE-a-zide |
| Amlodipine · am-LOE-di-peen |
| Benazepril · ben-AY-ze-pril |
| Enalapril · e-NAL-a-pril |
| Ramipril · RA-mi-pril |
Pronunciation is shown for the US English generic name. A name ending is a memory cue, not a classification rule.
Body system and related classes
Body system: Cardiovascular
How each medicine works
| Lisinopril — Inhibits angiotensin-converting enzyme, blocking conversion of angiotensin I to angiotensin II and suppressing the renin-angiotensin-aldosterone system. |
| Lisinopril / Hydrochlorothiazide — Lisinopril inhibits ACE, lowering angiotensin II and aldosterone; hydrochlorothiazide is a thiazide diuretic. |
| Amlodipine / Benazepril — Benazepril inhibits ACE, lowering angiotensin II and aldosterone; amlodipine is a dihydropyridine calcium channel blocker. |
| Benazepril — Benazeprilat inhibits ACE, blocking conversion of angiotensin I to angiotensin II and lowering aldosterone. |
| Enalapril — Hydrolyzed to enalaprilat, which inhibits ACE, blocking angiotensin II formation and aldosterone secretion. |
| Ramipril — Ramiprilat inhibits ACE, blocking conversion of angiotensin I to angiotensin II and reducing aldosterone. |
Each summary is the mechanism line from the medicine’s study card.
What each medicine is used for
| Lisinopril — Hypertension in adults and children aged 6 years and older; Adjunctive therapy for heart failure; Reduction of mortality after acute myocardial infarction in hemodynamically stable patients treated within 24 hours |
| Lisinopril / Hydrochlorothiazide — Hypertension when this fixed-dose combination is appropriate; it is not indicated for initial therapy |
| Amlodipine / Benazepril — Hypertension not controlled on monotherapy |
| Benazepril — Hypertension in adults and children aged 6 years and older; pediatric use is not established with GFR below 30 mL/min/1.73 m² |
| Enalapril — Hypertension in adults and children aged 1 month and older; not recommended in neonates or children with GFR below 30 mL/min/1.73 m²; Symptomatic heart failure, usually with diuretics and digitalis; Reduction of overt heart failure and related hospitalization in clinically stable, asymptomatic left ventricular dysfunction with ejection fraction at or below 35% |
| Ramipril — Hypertension in adults; Reduction of myocardial infarction, stroke or cardiovascular death in adults aged 55 years and older with coronary disease, prior stroke, peripheral vascular disease, or diabetes plus another labeled cardiovascular risk factor |
Each list is the uses line from the medicine’s study card.
Telling these medicines apart
Medicines in this class: 6 · single-ingredient: 4 · combination products: 2
Not in the reviewed -pril name-ending list: Lisinopril / Hydrochlorothiazide, Amlodipine / Benazepril
Also in other drug classes: Lisinopril / Hydrochlorothiazide (Thiazide and thiazide-like diuretics) · Amlodipine / Benazepril (Dihydropyridine calcium channel blockers)
Listed on more than one card in this class
Common side effects
Cough · 6/6: Lisinopril, Lisinopril / Hydrochlorothiazide, Amlodipine / Benazepril, Benazepril, Enalapril, Ramipril
Headache · 5/6: Lisinopril, Lisinopril / Hydrochlorothiazide, Benazepril, Enalapril, Ramipril
Dizziness · 5/6: Lisinopril, Lisinopril / Hydrochlorothiazide, Benazepril, Enalapril, Ramipril
Fatigue · 3/6: Lisinopril / Hydrochlorothiazide, Enalapril, Ramipril
Warnings
Angioedema · 3/6: Lisinopril, Benazepril, Ramipril
Renal impairment · 3/6: Lisinopril, Benazepril, Ramipril
Hyperkalemia · 2/6: Lisinopril, Benazepril
Hypotension and hyperkalemia · 2/6: Amlodipine / Benazepril, Enalapril
Interactions
NSAIDs · 4/6: Lisinopril, Amlodipine / Benazepril, Benazepril, Ramipril
Lithium · 3/6: Lisinopril, Amlodipine / Benazepril, Benazepril
Diuretics · 2/6: Lisinopril, Ramipril
Boxed warning
6/6: Lisinopril, Lisinopril / Hydrochlorothiazide, Amlodipine / Benazepril, Benazepril, Enalapril, Ramipril
Same boxed-warning wording on: Benazepril, Enalapril, Ramipril
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.