Amlodipine / Benazepril: study card

Amlodipine / Benazepril — Dihydropyridine CCB + ACE inhibitor combination. Study the mechanism, listed uses and warnings from the US label on one sourced card.

Generic name
Amlodipine / Benazepril
Class
Dihydropyridine CCB + ACE inhibitor combination
Mechanism
Benazepril inhibits ACE, lowering angiotensin II and aldosterone; amlodipine is a dihydropyridine calcium channel blocker.
Used for
Hypertension not controlled on monotherapy
Common side effects
Cough; Edema
Boxed warning
Fetal toxicity: renin-angiotensin system drugs can injure or kill the fetus; stop when pregnancy is detected.
Warnings
Angioedema / anaphylactoid reactions; Hypotension and hyperkalemia; Contraindicated with neprilysin inhibitors
Interactions
Potassium supplements / K-sparing diuretics; Lithium; NSAIDs

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

Drug class families: ACE inhibitors · Dihydropyridine calcium channel blockers

Read the source label ↗

Label date: 20260909 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.

Pronunciation

Amlodipine: am-LOE-di-peen · Benazepril: ben-AY-ze-pril

Pronunciation is shown for the US English generic name.

Other drugs in the same class

ACE inhibitors: Benazepril, Enalapril, Ramipril, Lisinopril, Lisinopril / Hydrochlorothiazide

Dihydropyridine calcium channel blockers: Amlodipine, Olmesartan / Amlodipine / Hydrochlorothiazide

Body system

Cardiovascular · 47 Drug cards

Compare with related cards

Lisinopril

Same class family: ACE inhibitors

Mechanism: Inhibits angiotensin-converting enzyme, blocking conversion of angiotensin I to angiotensin II and suppressing the renin-angiotensin-aldosterone system.

On both cards: Common side effects — Cough · Interactions — Lithium; NSAIDs

Only on the Lisinopril card: Used for — Hypertension in adults and children aged 6 years and older; Adjunctive therapy for heart failure; Reduction of mortality after acute myocardial infarction in hemodynamically stable patients treated within 24 hours · Common side effects — Headache; Dizziness; Hypotension; Chest pain · Warnings — Angioedema; Hyperkalemia; Renal impairment · Interactions — Diuretics

Benazepril

Same class family: ACE inhibitors

Mechanism: Benazeprilat inhibits ACE, blocking conversion of angiotensin I to angiotensin II and lowering aldosterone.

On both cards: Common side effects — Cough · Interactions — Lithium; NSAIDs

Only on the Benazepril card: Used for — Hypertension in adults and children aged 6 years and older; pediatric use is not established with GFR below 30 mL/min/1.73 m² · Common side effects — Headache; Dizziness; Somnolence; Postural dizziness · Warnings — Angioedema; Hyperkalemia; Renal impairment · Interactions — Neprilysin inhibitors (sacubitril)

Olmesartan / Amlodipine / Hydrochlorothiazide

Same class family: Dihydropyridine calcium channel blockers

Mechanism: Olmesartan blocks angiotensin II effects, amlodipine blocks calcium entry into vascular smooth muscle, and HCTZ promotes sodium and chloride excretion.

On both cards: Interactions — Lithium; NSAIDs

Only on the Olmesartan / Amlodipine / Hydrochlorothiazide card: Used for — Hypertension requiring the selected olmesartan/amlodipine/hydrochlorothiazide combination; not indicated for initial therapy · Common side effects — Dizziness; Peripheral edema; Headache; Fatigue; Muscle spasms · Warnings — Hypotension in volume-depleted patients; Fluid and electrolyte imbalance; Sprue-like enteropathy · Interactions — Aliskiren (in diabetes)

An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.

Boxed warnings on related cards

Lisinopril: Drugs acting on the renin-angiotensin system can cause fetal injury and death; discontinue when pregnancy is detected.

Lisinopril / Hydrochlorothiazide: Fetal toxicity: drugs acting on the renin-angiotensin system can injure or kill the developing fetus; stop when pregnancy is detected.

Olmesartan / Amlodipine / Hydrochlorothiazide: Fetal toxicity: drugs acting on the renin-angiotensin system can injure or kill the fetus; stop when pregnancy is detected.

Benazepril: Fetal toxicity: discontinue as soon as pregnancy is detected.