CapseraP2Y12 platelet inhibitors
Compare the named medicines in this source-linked class directory.
Membership describes a named action or a component of a combination. A medicine may appear in several families. Medicines in one family are not automatically interchangeable; this is a study directory, not a prescribing guide.
No matching drugs. Try another name.
Generic names and pronunciation
| Clopidogrel · kloh-PID-oh-grel |
| Ticagrelor · tye-KA-grel-or |
Pronunciation is shown for the US English generic name.
Body system and related classes
Body systems: Cardiovascular · Hematology
How each medicine works
| Clopidogrel — Prodrug; active metabolite irreversibly binds P2Y12 ADP receptors on platelets, inhibiting platelet activation and aggregation. |
| Ticagrelor — Reversibly binds the platelet P2Y12 ADP receptor, preventing signal transduction and platelet activation. |
Each summary is the mechanism line from the medicine’s study card.
What each medicine is used for
| Clopidogrel — Acute coronary syndrome (NSTE-ACS, STEMI); Recent MI, recent stroke; Established peripheral arterial disease |
| Ticagrelor — Reduction of cardiovascular death, myocardial infarction and stroke risk in adults with acute coronary syndrome or prior myocardial infarction; Reduction of stent thrombosis in adults stented for acute coronary syndrome |
Each list is the uses line from the medicine’s study card.
Telling these medicines apart
Medicines in this class: 2
By body system: Cardiovascular (Ticagrelor) · Hematology (Clopidogrel)
Listed on more than one card in this class
Common side effects
Bleeding · 2/2: Clopidogrel, Ticagrelor
Interactions
Opioids · 2/2: Clopidogrel, Ticagrelor
Boxed warning
2/2: Clopidogrel, Ticagrelor
Listed on only one card in this class
Clopidogrel: Common side effects — Epistaxis; Hematuria; Bruising · Warnings — Avoid omeprazole or esomeprazole; Bleeding risk; Premature discontinuation raises CV risk · Interactions — Omeprazole, esomeprazole (CYP2C19 inhibitors); NSAIDs, warfarin, SSRIs, SNRIs
Ticagrelor: Common side effects — Dyspnea · Warnings — Dyspnea; Severe hepatic impairment; False-negative HIT platelet function tests · Interactions — Strong CYP3A inhibitors / inducers; Simvastatin / lovastatin
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.