Norelgestromin / Ethinyl Estradiol: study card

Norelgestromin / Ethinyl Estradiol — Combination hormonal contraceptive (transdermal patch). Study the mechanism, listed uses and warnings from the US label on one sourced card.

Generic name
Norelgestromin / Ethinyl Estradiol
Class
Combination hormonal contraceptive (transdermal patch)
Mechanism
Suppresses gonadotropins, mainly inhibiting ovulation; also alters cervical mucus and endometrium. Norelgestromin is the active metabolite of norgestimate.
Used for
Prevention of pregnancy when a combined hormonal contraceptive is appropriate and BMI is below 30 kg/m2; may be less effective at body weight 90 kg or more
Common side effects
Breast symptoms; Nausea / vomiting; Headache; Application site reaction; Dysmenorrhea
Boxed warning
Smoking raises serious cardiovascular risk; contraindicated in women over 35 who smoke and in women with BMI of 30 kg/m2 or more.
Warnings
Thromboembolic events (VTE, MI, stroke); Liver disease / jaundice; Uncontrolled hypertension
Interactions
CYP3A4 inducers incl. St. John's wort; Ombitasvir/paritaprevir/ritonavir (HCV); CYP3A4 inhibitors (azole antifungals)

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

Read the source label ↗

Label date: 20260416 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.

Pronunciation

Norelgestromin: nor-el-JES-troe-min · Ethinyl Estradiol: ETH-in-il es-tra-DYE-ol

Pronunciation is shown for the US English generic name.

Body system

Women's health · 12 Drug cards

Compare with related cards

Norethindrone / Ethinyl Estradiol

Same body system: Women's health

Mechanism: Combined hormonal contraceptive that lowers pregnancy risk primarily by suppressing ovulation.

On both cards: Common side effects — Nausea / vomiting; Dysmenorrhea · Warnings — Uncontrolled hypertension

Only on the Norethindrone / Ethinyl Estradiol card: Used for — Prevention of pregnancy in females of reproductive potential; efficacy of the selected Kaitlib Fe product at BMI above 35 kg/m² has not been evaluated · Common side effects — Headache / migraine; Mood complaints; Acne · Warnings — Arterial / venous thrombotic events; Liver disease; breast cancer · Interactions — CYP3A4 inducers (e.g., rifampin, carbamazepine); HIV protease inhibitors / NNRTIs; Ombitasvir/paritaprevir/ritonavir

Etonogestrel / Ethinyl Estradiol

Same body system: Women's health

Mechanism: Suppresses gonadotropins to inhibit ovulation; also alters cervical mucus and endometrium.

On both cards: Common side effects — Nausea / vomiting; Headache · Warnings — Liver disease / jaundice

Only on the Etonogestrel / Ethinyl Estradiol card: Used for — Prevention of pregnancy · Common side effects — Vaginitis; Mood changes; Device-related events · Warnings — Thrombotic / vascular events; Toxic shock syndrome · Interactions — CYP3A4 inducers

Levonorgestrel / Ethinyl Estradiol

Same body system: Women's health

Mechanism: Prevents pregnancy primarily by suppressing ovulation.

On both cards: Common side effects — Headache; Dysmenorrhea

Only on the Levonorgestrel / Ethinyl Estradiol card: Used for — Prevention of pregnancy · Common side effects — Menorrhagia; Nausea; Breast tenderness · Warnings — Thrombotic and thromboembolic events; Liver disease; Hypertension · Interactions — Enzyme inducers (reduced efficacy)

An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.

Boxed warnings on related cards

Other cards with a boxed warning in this body system (Women's health): Norethindrone / Ethinyl Estradiol, Estradiol (transdermal), Norgestimate / Ethinyl Estradiol, Progesterone, Estradiol (topical), Levonorgestrel / Ethinyl Estradiol, Drospirenone / Ethinyl estradiol, Etonogestrel / Ethinyl Estradiol, Desogestrel / Ethinyl Estradiol, Medroxyprogesterone