Etonogestrel / Ethinyl Estradiol: brand names and study card
Etonogestrel / Ethinyl Estradiol — Combination hormonal contraceptive (vaginal ring). Study the mechanism, listed uses and warnings from the US label on one sourced card.
Generic name
Etonogestrel / Ethinyl Estradiol
Brands
NuvaRing
Class
Combination hormonal contraceptive (vaginal ring)
Mechanism
Suppresses gonadotropins to inhibit ovulation; also alters cervical mucus and endometrium.
Label date: 20251114 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Combination oral contraceptive that prevents pregnancy primarily by suppressing ovulation.
On both cards: Used for — Prevention of pregnancy · Common side effects — Mood changes; Nausea / vomiting
Only on the Drospirenone / Ethinyl estradiol card: Common side effects — Premenstrual syndrome; Headache / migraine; Breast pain / tenderness · Warnings — Drospirenone-containing COCs may have a higher VTE risk than levonorgestrel-containing or some other COCs; Hyperkalemia risk due to anti-mineralocorticoid activity; Liver disease · Interactions — CYP3A4 inducers (reduced efficacy); Hepatitis C combos with ombitasvir/paritaprevir; Potassium-raising drugs
Mechanism: Suppresses gonadotropins, mainly inhibiting ovulation; also alters cervical mucus and endometrium. Norelgestromin is the active metabolite of norgestimate.
On both cards: Common side effects — Headache; Nausea / vomiting · Warnings — Liver disease / jaundice
Only on the Norelgestromin / Ethinyl Estradiol card: Used for — Prevention of pregnancy when a combined hormonal contraceptive is appropriate and BMI is below 30 kg/m2; may be less effective at body weight 90 kg or more · Common side effects — Breast symptoms; Application site reaction; Dysmenorrhea · Warnings — Thromboembolic events (VTE, MI, stroke); Uncontrolled hypertension · Interactions — CYP3A4 inducers incl. St. John's wort; Ombitasvir/paritaprevir/ritonavir (HCV); CYP3A4 inhibitors (azole antifungals)
Mechanism: Primarily suppresses ovulation; possible additional mechanisms include cervical-mucus changes that inhibit sperm penetration and endometrial changes that reduce implantation likelihood.
On both cards: Used for — Prevention of pregnancy · Warnings — Liver disease / jaundice
Only on the Norgestimate / Ethinyl Estradiol card: Common side effects — Headache / migraine; Abdominal pain; Breast tenderness; Nausea; Irregular uterine bleeding · Warnings — Thromboembolic disorders; Hypertension · Interactions — CYP3A4 inducers (reduced efficacy)
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.
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