Desogestrel / Ethinyl Estradiol: study card

Desogestrel / Ethinyl Estradiol — Combined oral contraceptive. Study the mechanism, listed uses and warnings from the US label on one sourced card.

Generic name
Desogestrel / Ethinyl Estradiol
Class
Combined oral contraceptive
Mechanism
Suppresses gonadotropins, mainly inhibiting ovulation; also alters cervical mucus and endometrium.
Used for
Prevention of pregnancy
Common side effects
Nausea; Vomiting; Breakthrough bleeding / spotting; Breast tenderness; Change in weight
Boxed warning
Cigarette smoking raises serious cardiovascular risk; not for women over 35 who smoke.
Warnings
Thromboembolic disorders (contraindicated); Cerebrovascular or coronary artery disease
Interactions
CYP3A4 inducers

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

Read the source label ↗

Label date: 20260812 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.

Pronunciation

Desogestrel: des-oh-JES-trel · Ethinyl Estradiol: ETH-in-il es-tra-DYE-ol

Pronunciation is shown for the US English generic name.

Body system

Women's health · 12 Drug cards

Compare with related cards

Norgestimate / Ethinyl Estradiol

Same body system: Women's health

Mechanism: Primarily suppresses ovulation; possible additional mechanisms include cervical-mucus changes that inhibit sperm penetration and endometrial changes that reduce implantation likelihood.

On both cards: Used for — Prevention of pregnancy · Common side effects — Nausea; Breast tenderness

Only on the Norgestimate / Ethinyl Estradiol card: Common side effects — Headache / migraine; Abdominal pain; Irregular uterine bleeding · Warnings — Thromboembolic disorders; Liver disease / jaundice; Hypertension · Interactions — CYP3A4 inducers (reduced efficacy)

Norethindrone

Same body system: Women's health

Mechanism: Suppresses ovulation in about half of users, thickens cervical mucus, blunts LH/FSH peaks and alters the endometrium.

On both cards: Used for — Prevention of pregnancy · Common side effects — Nausea; Breast tenderness

Only on the Norethindrone card: Common side effects — Menstrual irregularity; Headache; Dizziness · Warnings — Known or suspected pregnancy (contraindicated); Breast carcinoma (contraindicated); Liver tumors or acute liver disease · Interactions — CYP3A4 inducers (reduced efficacy)

Levonorgestrel / Ethinyl Estradiol

Same body system: Women's health

Mechanism: Prevents pregnancy primarily by suppressing ovulation.

On both cards: Used for — Prevention of pregnancy · Common side effects — Nausea; Breast tenderness

Only on the Levonorgestrel / Ethinyl Estradiol card: Common side effects — Headache; Menorrhagia; Dysmenorrhea · Warnings — Thrombotic and thromboembolic events; Liver disease; Hypertension · Interactions — Enzyme inducers (reduced efficacy)

An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.

Boxed warnings on related cards

Other cards with a boxed warning in this body system (Women's health): Norethindrone / Ethinyl Estradiol, Estradiol (transdermal), Norgestimate / Ethinyl Estradiol, Progesterone, Estradiol (topical), Levonorgestrel / Ethinyl Estradiol, Drospirenone / Ethinyl estradiol, Etonogestrel / Ethinyl Estradiol, Medroxyprogesterone, Norelgestromin / Ethinyl Estradiol