Butalbital / Acetaminophen / Caffeine — Barbiturate + analgesic + methylxanthine combination. Study the mechanism, listed uses and warnings from the US label on one sourced card.
Fixed combination for tension headache; the role of each component is incompletely understood.
Used for
Relief of tension (muscle-contraction) headache symptoms in adults and patients aged 12 years and older
Common side effects
Drowsiness; Lightheadedness; Dizziness; Nausea / vomiting; Shortness of breath
Boxed warning
Acetaminophen has been associated with acute liver failure, at times resulting in transplant or death.
Warnings
Butalbital is habit-forming; Porphyria (contraindicated); Evidence for safety and effectiveness in multiple recurrent headaches is unavailable; butalbital can cause dependence and misuse.
Interactions
MAO inhibitors; Alcohol; Other CNS depressants
Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.
Label date: 20260713 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Codeine is a mu-opioid agonist with weaker receptor affinity than morphine. Conversion to morphine may explain its analgesia, but the exact mechanism is unknown. Acetaminophen’s analgesic mechanism is not established and is thought to involve central actions.
On both cards: Common side effects — Drowsiness; Nausea / vomiting; Shortness of breath
Only on the Acetaminophen / Codeine card: Used for — Mild-to-moderate pain when an opioid is appropriate and alternative treatments are inadequate · Common side effects — Lightheadedness / dizziness; Constipation · Warnings — Contraindicated in children younger than 12; Significant respiratory depression is a contraindication; Contraindicated for postoperative pain in children younger than 18 after tonsillectomy or adenoidectomy · Interactions — CYP2D6 inhibitors; CYP3A4 inhibitors; Benzodiazepines / other CNS depressants
Mechanism: Oxycodone is a full opioid agonist with relative mu-receptor selectivity; its analgesic action involves CNS opioid receptors. Although analgesia has no fixed ceiling, clinical dosing is limited by toxicity including respiratory/CNS depression. Acetaminophen has an unestablished analgesic mechanism thought to involve central actions.
On both cards: Common side effects — Lightheadedness; Dizziness
Only on the Oxycodone / Acetaminophen card: Used for — Pain severe enough to require an opioid analgesic when alternative treatments are inadequate · Common side effects — Drowsiness / sedation; Nausea; Vomiting · Warnings — Significant respiratory depression; Acute or severe bronchial asthma in an unmonitored setting or without resuscitative equipment; GI obstruction including paralytic ileus · Interactions — CYP3A4 / CYP2D6 inhibitors; CYP3A4 inducers; Benzodiazepines / CNS depressants
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.
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