Capsera5-HT1B/1D receptor agonists
Compare the named medicines in this source-linked class directory.
Membership describes a named action or a component of a combination. A medicine may appear in several families. Medicines in one family are not automatically interchangeable; this is a study directory, not a prescribing guide.
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Generic names and pronunciation
Shared name ending: -triptan · Sumatriptan, Rizatriptan
| Sumatriptan · soo-ma-TRIP-tan |
| Rizatriptan · rye-za-TRIP-tan |
Pronunciation is shown for the US English generic name. A name ending is a memory cue, not a classification rule.
Body system and related classes
Body system: Neurology
How each medicine works
| Sumatriptan — Presumed to act in migraine through 5-HT1B/1D agonism on intracranial vessels and trigeminal sensory nerves, producing cranial vasoconstriction and reduced pro-inflammatory neuropeptide release. |
| Rizatriptan — Presumed to treat migraine by binding 5-HT1B/1D receptors on intracranial blood vessels and sensory nerves of the trigeminal system. |
Each summary is the mechanism line from the medicine’s study card.
What each medicine is used for
| Sumatriptan — Acute treatment of migraine with or without aura in adults |
| Rizatriptan — Acute migraine with or without aura in adults and children aged 6–17 after a clear migraine diagnosis; not migraine prevention |
Each list is the uses line from the medicine’s study card.
Telling these medicines apart
Medicines in this class: 2
Listed on only one card in this class
Sumatriptan: Common side effects — Paresthesia; Warm/cold sensation; Chest pain / tightness; Neck/throat/jaw pressure; Vertigo · Warnings — Contraindicated in ischemic or vasospastic CAD; Stroke / TIA, WPW, uncontrolled hypertension; Serotonin syndrome; medication overuse headache · Interactions — Ergot-containing drugs / other 5-HT1 agonists; MAO-A inhibitors; SSRIs / SNRIs (serotonin syndrome)
Rizatriptan: Common side effects — Asthenia / fatigue; Somnolence; Pain / pressure sensation; Dizziness · Warnings — Myocardial ischemia / infarction, Prinzmetal's angina; Stroke and cerebral hemorrhage; Serotonin syndrome · Interactions — Propranolol; Ergot-containing drugs; Other 5-HT1 agonists
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.