Sumatriptan: study card

Sumatriptan — Serotonin 5-HT1B/1D receptor agonist (triptan). Study the mechanism, listed uses and warnings from the US label on one sourced card.

Generic name: Sumatriptan
Class: Serotonin 5-HT1B/1D receptor agonist (triptan)
Mechanism: Presumed to act in migraine through 5-HT1B/1D agonism on intracranial vessels and trigeminal sensory nerves, producing cranial vasoconstriction and reduced pro-inflammatory neuropeptide release.
Used for: Acute treatment of migraine with or without aura in adults
Common side effects: Paresthesia; Warm/cold sensation; Chest pain / tightness; Neck/throat/jaw pressure; Vertigo
Warnings: Contraindicated in ischemic or vasospastic CAD; Stroke / TIA, WPW, uncontrolled hypertension; Serotonin syndrome; medication overuse headache
Interactions: Ergot-containing drugs / other 5-HT1 agonists; MAO-A inhibitors; SSRIs / SNRIs (serotonin syndrome)

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

Drug class families: 5-HT1B/1D receptor agonists

Read the source label ↗

Label date: 20260902 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.

Practice

Pronunciation

Sumatriptan: soo-ma-TRIP-tan

Shared name ending: -triptan · Rizatriptan

Pronunciation is shown for the US English generic name. A name ending is a memory cue, not a classification rule.

Other drugs in the same class

5-HT1B/1D receptor agonists: Rizatriptan

Body system

Neurology · 18 Drug cards

Compare with related cards

Rizatriptan

Same class family: 5-HT1B/1D receptor agonists

Mechanism: Presumed to treat migraine by binding 5-HT1B/1D receptors on intracranial blood vessels and sensory nerves of the trigeminal system.

Only on the Rizatriptan card: Used for — Acute migraine with or without aura in adults and children aged 6–17 after a clear migraine diagnosis; not migraine prevention · Common side effects — Asthenia / fatigue; Somnolence; Pain / pressure sensation; Dizziness · Warnings — Myocardial ischemia / infarction, Prinzmetal's angina; Stroke and cerebral hemorrhage; Serotonin syndrome · Interactions — Propranolol; Ergot-containing drugs; Other 5-HT1 agonists

An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.