CapseraDopamine receptor agonists
Compare the named medicines in this source-linked class directory.
Membership describes a named action or a component of a combination. A medicine may appear in several families. Medicines in one family are not automatically interchangeable; this is a study directory, not a prescribing guide.
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Generic names and pronunciation
| Ropinirole · roe-PIN-i-role |
| Pramipexole · pram-i-PEX-ole |
Pronunciation is shown for the US English generic name.
Body system and related classes
Body system: Neurology
How each medicine works
| Ropinirole — Non-ergoline dopamine agonist thought to act by stimulating D2 receptors in the caudate-putamen. |
| Pramipexole — Non-ergot dopamine agonist with in-vitro activity at D2-family receptors and greater affinity for D3 than D2 or D4. The precise mechanisms in Parkinson disease and restless legs syndrome are unknown. |
Each summary is the mechanism line from the medicine’s study card.
What each medicine is used for
| Ropinirole — Parkinson's disease; Moderate-to-severe primary restless legs syndrome |
| Pramipexole — Parkinson disease in adults; Moderate-to-severe primary restless legs syndrome in adults |
Each list is the uses line from the medicine’s study card.
Telling these medicines apart
Medicines in this class: 2
Listed on more than one card in this class
Common side effects
Nausea · 2/2: Ropinirole, Pramipexole
Somnolence · 2/2: Ropinirole, Pramipexole
Dizziness · 2/2: Ropinirole, Pramipexole
Hallucinations · 2/2: Ropinirole, Pramipexole
Warnings
Falling asleep during daily activities · 2/2: Ropinirole, Pramipexole
Impulse control / compulsive behaviors · 2/2: Ropinirole, Pramipexole
Listed on only one card in this class
Ropinirole: Common side effects — Syncope · Warnings — Orthostatic hypotension / syncope · Interactions — CYP1A2 inhibitors or inducers; Hormone replacement therapy; Dopamine antagonists
Pramipexole: Common side effects — Insomnia · Warnings — Orthostatic hypotension · Interactions — Dopamine antagonists (neuroleptics, metoclopramide)
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.