- Generic name
- Amiodarone
- Class
- Class III antiarrhythmic
- Mechanism
- Class III antiarrhythmic with properties of all four Vaughan Williams classes; blocks Na+ channels, antisympathetic.
- Used for
- Documented, life-threatening recurrent ventricular fibrillation in adults after inadequate response to other antiarrhythmics or inability to tolerate alternatives; Documented, life-threatening recurrent hemodynamically unstable ventricular tachycardia in adults under the same treatment restrictions
- Common side effects
- Pulmonary infiltrates / fibrosis; Paroxysmal ventricular tachycardia; Congestive heart failure; Elevated liver enzymes
- Boxed warning
- Pulmonary, hepatic and cardiac toxicity; reserved for life-threatening arrhythmias.
- Warnings
- Thyroid abnormalities (hypo/hyper); Visual impairment / optic neuropathy; Effects persist weeks after stopping
- Interactions
- QT-prolonging drugs; Digoxin; Beta-blockers / verapamil / diltiazem
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Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.