Label date: 20260824 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Selectively blocks angiotensin II binding to AT1 receptors, inhibiting its vasoconstrictor and aldosterone-secreting effects.
On both cards: Common side effects — Hyperkalemia; Dizziness · Interactions — Lithium
Only on the Valsartan card: Used for — Hypertension in adults and children aged 6 years and older; Reduction of heart-failure hospitalization in adults with NYHA class II–IV heart failure; Reduction of cardiovascular mortality in clinically stable adults with left ventricular failure or dysfunction after myocardial infarction · Common side effects — Headache; Fatigue; Hypotension · Warnings — Hypotension; Renal function and potassium changes; No aliskiren in diabetes · Interactions — Potassium-sparing diuretics / supplements; NSAIDs
On both cards: Common side effects — Hyperkalemia; Dizziness · Interactions — Lithium
Only on the Sacubitril / Valsartan card: Used for — Reduction of cardiovascular death and heart-failure hospitalization in adults with chronic heart failure; benefit is most evident when LVEF is below normal; Symptomatic heart failure with systemic left ventricular systolic dysfunction in children aged 1 year and older · Common side effects — Hypotension; Cough; Renal failure · Warnings — Angioedema; Hypotension; Renal impairment / hyperkalemia · Interactions — ACE inhibitors (contraindicated); Potassium-sparing diuretics
Mechanism: Losartan and its active metabolite block the vasoconstrictor and aldosterone-secreting effects of angiotensin II at its receptor.
On both cards: Common side effects — Dizziness · Interactions — Lithium
Only on the Losartan card: Used for — Hypertension in adults and children aged 6 years and older; Stroke-risk reduction in hypertension with left ventricular hypertrophy; the label reports that this benefit did not apply to Black patients; Diabetic nephropathy with elevated serum creatinine and proteinuria in type 2 diabetes with a history of hypertension · Common side effects — Upper respiratory infection; Nasal congestion; Back pain · Warnings — Hypotension in volume-depleted patients; Renal function changes; Hyperkalemia · Interactions — Potassium-raising agents; NSAIDs
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.
Losartan: Drugs acting on the renin-angiotensin system can cause fetal injury and death; discontinue when pregnancy is detected.
Losartan / Hydrochlorothiazide: Fetal toxicity: drugs acting on the renin-angiotensin system can injure or kill the developing fetus; stop when pregnancy is detected.
Valsartan: Fetal toxicity: drugs acting on the renin-angiotensin system can injure or kill the developing fetus; stop when pregnancy is detected.
Telmisartan: Fetal toxicity: discontinue as soon as pregnancy is detected.
Capsera