Valsartan — Angiotensin II receptor blocker (ARB). Study the mechanism, listed uses and warnings from the US label on one sourced card.
Generic name
Valsartan
Brands
Diovan
Class
Angiotensin II receptor blocker (ARB)
Mechanism
Selectively blocks angiotensin II binding to AT1 receptors, inhibiting its vasoconstrictor and aldosterone-secreting effects.
Used for
Hypertension in adults and children aged 6 years and older; Reduction of heart-failure hospitalization in adults with NYHA class II–IV heart failure; Reduction of cardiovascular mortality in clinically stable adults with left ventricular failure or dysfunction after myocardial infarction
Label date: 20260805 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Olmesartan blocks angiotensin II effects, amlodipine blocks calcium entry into vascular smooth muscle, and HCTZ promotes sodium and chloride excretion.
On both cards: Common side effects — Headache; Dizziness; Fatigue · Interactions — NSAIDs; Lithium
Only on the Olmesartan / Amlodipine / Hydrochlorothiazide card: Used for — Hypertension requiring the selected olmesartan/amlodipine/hydrochlorothiazide combination; not indicated for initial therapy · Common side effects — Peripheral edema; Muscle spasms · Warnings — Hypotension in volume-depleted patients; Fluid and electrolyte imbalance; Sprue-like enteropathy · Interactions — Aliskiren (in diabetes)
On both cards: Common side effects — Dizziness; Hypotension; Hyperkalemia · Warnings — Hypotension · Interactions — Lithium
Only on the Sacubitril / Valsartan card: Used for — Reduction of cardiovascular death and heart-failure hospitalization in adults with chronic heart failure; benefit is most evident when LVEF is below normal; Symptomatic heart failure with systemic left ventricular systolic dysfunction in children aged 1 year and older · Common side effects — Cough; Renal failure · Warnings — Angioedema; Renal impairment / hyperkalemia · Interactions — ACE inhibitors (contraindicated); Potassium-sparing diuretics
Mechanism: Losartan and its active metabolite block the vasoconstrictor and aldosterone-secreting effects of angiotensin II at its receptor.
On both cards: Used for — Hypertension in adults and children aged 6 years and older · Common side effects — Dizziness · Interactions — NSAIDs; Lithium
Only on the Losartan card: Used for — Stroke-risk reduction in hypertension with left ventricular hypertrophy; the label reports that this benefit did not apply to Black patients; Diabetic nephropathy with elevated serum creatinine and proteinuria in type 2 diabetes with a history of hypertension · Common side effects — Upper respiratory infection; Nasal congestion; Back pain · Warnings — Hypotension in volume-depleted patients; Renal function changes; Hyperkalemia · Interactions — Potassium-raising agents
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.
Capsera