Macrolide antibacterials

Compare the named medicines in this source-linked class directory.

Membership describes a named action or a component of a combination. A medicine may appear in several families. Medicines in one family are not automatically interchangeable; this is a study directory, not a prescribing guide.

Azithromycin
Erythromycin (ophthalmic ointment)

Generic names and pronunciation

Azithromycin · az-ITH-roe-MYE-sin
Erythromycin (ophthalmic ointment) · e-rith-roe-MYE-sin

Pronunciation is shown for the US English generic name.

Body system and related classes

Body systems: Infectious disease · Eye & ear

How each medicine works

Azithromycin — Binds to the bacterial 50S ribosomal subunit and interrupts protein synthesis.
Erythromycin (ophthalmic ointment) — Macrolide that inhibits bacterial protein synthesis without affecting nucleic acid synthesis.

Each summary is the mechanism line from the medicine’s study card.

What each medicine is used for

Azithromycin — Community-acquired pneumonia caused by the specified susceptible bacteria in adults or children aged 6 months and older who are appropriate for oral treatment; Streptococcal pharyngitis or tonsillitis in adults or children aged 2 years and older who cannot use first-line therapy; Acute otitis media caused by the specified susceptible bacteria in children aged 6 months and older; Urethritis or cervicitis caused by the specified susceptible organisms in adults
Erythromycin (ophthalmic ointment) — Superficial conjunctival or corneal infections caused by erythromycin-susceptible organisms; Ophthalmia neonatorum prophylaxis as listed in the selected label; topical prophylaxis alone is inadequate for infants of mothers with clinically apparent gonorrhea

Each list is the uses line from the medicine’s study card.

Telling these medicines apart

Medicines in this class: 2

By body system: Infectious disease (Azithromycin) · Eye & ear (Erythromycin (ophthalmic ointment))

Listed on only one card in this class

Azithromycin: Common side effects — Diarrhea; Nausea; Abdominal pain; Vomiting · Warnings — Serious allergic and skin reactions; Hepatotoxicity; QT prolongation / torsades de pointes

Erythromycin (ophthalmic ointment): Common side effects — Minor ocular irritation; Redness; Hypersensitivity reactions · Warnings — Hypersensitivity to erythromycin

An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.