Macrolide antibacterials
Compare the named medicines in this source-linked class directory.
Membership describes a named action or a component of a combination. A medicine may appear in several families. Medicines in one family are not automatically interchangeable; this is a study directory, not a prescribing guide.
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Generic names and pronunciation
| Azithromycin · az-ITH-roe-MYE-sin |
| Erythromycin (ophthalmic ointment) · e-rith-roe-MYE-sin |
Pronunciation is shown for the US English generic name.
Body system and related classes
Body systems: Infectious disease · Eye & ear
How each medicine works
| Azithromycin — Binds to the bacterial 50S ribosomal subunit and interrupts protein synthesis. |
| Erythromycin (ophthalmic ointment) — Macrolide that inhibits bacterial protein synthesis without affecting nucleic acid synthesis. |
Each summary is the mechanism line from the medicine’s study card.
What each medicine is used for
| Azithromycin — Community-acquired pneumonia caused by the specified susceptible bacteria in adults or children aged 6 months and older who are appropriate for oral treatment; Streptococcal pharyngitis or tonsillitis in adults or children aged 2 years and older who cannot use first-line therapy; Acute otitis media caused by the specified susceptible bacteria in children aged 6 months and older; Urethritis or cervicitis caused by the specified susceptible organisms in adults |
| Erythromycin (ophthalmic ointment) — Superficial conjunctival or corneal infections caused by erythromycin-susceptible organisms; Ophthalmia neonatorum prophylaxis as listed in the selected label; topical prophylaxis alone is inadequate for infants of mothers with clinically apparent gonorrhea |
Each list is the uses line from the medicine’s study card.
Telling these medicines apart
Medicines in this class: 2
By body system: Infectious disease (Azithromycin) · Eye & ear (Erythromycin (ophthalmic ointment))
Listed on only one card in this class
Azithromycin: Common side effects — Diarrhea; Nausea; Abdominal pain; Vomiting · Warnings — Serious allergic and skin reactions; Hepatotoxicity; QT prolongation / torsades de pointes
Erythromycin (ophthalmic ointment): Common side effects — Minor ocular irritation; Redness; Hypersensitivity reactions · Warnings — Hypersensitivity to erythromycin
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.