CapseraPenicillin antibacterials
Compare the named medicines in this source-linked class directory.
Membership describes a named action or a component of a combination. A medicine may appear in several families. Medicines in one family are not automatically interchangeable; this is a study directory, not a prescribing guide.
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Combination: membership refers to the relevant component.
Generic names and pronunciation
| Amoxicillin · a-MOX-i-SIL-in |
| Clavulanate · KLAV-yoo-la-nate |
| Penicillin V potassium · pen-i-SIL-in VEE |
Pronunciation is shown for the US English generic name.
Body system and related classes
Body system: Infectious disease
How each medicine works
| Amoxicillin — Interferes with bacterial cell-wall formation, killing susceptible organisms while they are actively multiplying. |
| Amoxicillin / Clavulanate — Amoxicillin has bactericidal activity against susceptible bacteria. Clavulanate inactivates some beta-lactamases, protecting amoxicillin from those enzymes and extending its antibacterial spectrum. |
| Penicillin V potassium — Bactericidal during active multiplication by inhibiting cell-wall mucopeptide synthesis; inactive against penicillinase producers. |
Each summary is the mechanism line from the medicine’s study card.
What each medicine is used for
| Amoxicillin — Ear, nose and throat infections caused by the specified susceptible beta-lactamase-negative bacteria; Genitourinary infections caused by the specified susceptible beta-lactamase-negative bacteria; Skin and skin-structure infections caused by the specified susceptible beta-lactamase-negative bacteria; Lower respiratory infections caused by the specified susceptible beta-lactamase-negative bacteria |
| Amoxicillin / Clavulanate — Lower respiratory infections caused by the specified susceptible bacteria; Acute bacterial otitis media or sinusitis caused by the specified susceptible bacteria; Skin and skin-structure infections caused by the specified susceptible bacteria; Urinary tract infections caused by the specified susceptible bacteria; the combination is not indicated when testing shows amoxicillin susceptibility without beta-lactamase production |
| Penicillin V potassium — Mild-to-moderate streptococcal upper-respiratory infections without bacteremia, scarlet fever and mild erysipelas; Selected mild-to-moderately severe infections due to penicillin-G-sensitive organisms; severe invasive infections are not treated with oral penicillin V in the acute stage |
Each list is the uses line from the medicine’s study card.
Telling these medicines apart
Medicines in this class: 3 · single-ingredient: 2 · combination products: 1
Listed on more than one card in this class
Common side effects
Vomiting · 3/3: Amoxicillin, Amoxicillin / Clavulanate, Penicillin V potassium
Nausea · 3/3: Amoxicillin, Amoxicillin / Clavulanate, Penicillin V potassium
Diarrhea · 2/3: Amoxicillin, Penicillin V potassium
Warnings
C. difficile-associated diarrhea · 2/3: Amoxicillin, Amoxicillin / Clavulanate
Interactions
Probenecid · 2/3: Amoxicillin, Amoxicillin / Clavulanate
Oral anticoagulants · 2/3: Amoxicillin, Amoxicillin / Clavulanate
Allopurinol · 2/3: Amoxicillin, Amoxicillin / Clavulanate
Listed on only one card in this class
Amoxicillin: Common side effects — Rash · Warnings — Anaphylactic reactions; Severe cutaneous adverse reactions
Amoxicillin / Clavulanate: Common side effects — Diarrhea / loose stools; Skin rash, urticaria; Vaginitis · Warnings — Serious hypersensitivity reactions; Hepatic dysfunction, cholestatic jaundice
Penicillin V potassium: Common side effects — Epigastric distress; Black hairy tongue · Warnings — Hypersensitivity reactions, including potentially fatal anaphylaxis; A previous hypersensitivity reaction to any penicillin is a contraindication
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.