Ofloxacin (otic) — Fluoroquinolone antibacterial. Study the mechanism, listed uses and warnings from the US label on one sourced card.
Generic name
Ofloxacin
Class
Fluoroquinolone antibacterial
Mechanism
Fluoroquinolone that inhibits bacterial DNA gyrase, a topoisomerase needed for DNA replication, repair, and transcription.
Used for
Otitis externa from labeled susceptible bacteria in adults and children aged 6 months and older; Chronic suppurative otitis media from labeled susceptible bacteria with perforated tympanic membranes in patients aged 12 years and older; Acute otitis media from labeled susceptible bacteria in children aged 1 year and older with tympanostomy tubes
Common side effects
Application site reaction; Pruritus; Earache; Dizziness
Warnings
Hypersensitivity to quinolones (contraindicated)
Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.
Label date: 20260831 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Quinolone antimicrobial active against susceptible gram-positive and gram-negative bacteria causing eye infections.
On both cards: Warnings — Hypersensitivity to quinolones (contraindicated)
Only on the Ofloxacin (ophthalmic) card: Used for — Bacterial conjunctivitis caused by listed susceptible organisms; safety and effectiveness below age 1 are not established; Bacterial corneal ulcers caused by listed susceptible organisms; safety and effectiveness below age 1 are not established · Common side effects — Transient ocular burning / discomfort; Stinging; Redness; Itching; Photophobia
Mechanism: Fluoroquinolone antibacterial active against designated susceptible bacteria.
On both cards: Common side effects — Dizziness
Only on the Levofloxacin card: Used for — Adult nosocomial or community-acquired pneumonia caused by the specified susceptible organisms; Adult complicated UTI; uncomplicated UTI only when no alternative treatment options exist; Adult acute bacterial sinusitis only when no alternative treatment options exist; Post-exposure inhalational anthrax and treatment/prophylaxis of plague in adults and children aged 6 months or older; pediatric formulation/weight restrictions apply · Common side effects — Nausea; Headache; Diarrhea; Insomnia · Warnings — QT prolongation; Hepatotoxicity; C. difficile-associated diarrhea
Mechanism: Inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, disrupting processes required for bacterial DNA replication and maintenance.
Only on the Ciprofloxacin card: Used for — UTIs due to specified susceptible bacteria in adults, and selected complicated UTI/pyelonephritis in children aged 1–17; acute uncomplicated cystitis use is reserved for patients without alternatives; Specified susceptible lower-respiratory infections in adults; acute chronic-bronchitis exacerbation use is reserved for patients without alternatives; Specified susceptible skin, bone and joint infections in adults; Post-exposure inhalational anthrax and source-specified plague treatment/prevention in adults and children · Common side effects — Nausea; Diarrhea; Abnormal liver function tests; Vomiting; Rash · Warnings — QT prolongation; Hepatotoxicity; C. difficile-associated diarrhea
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.