Ofloxacin (ophthalmic) — Fluoroquinolone antibacterial (ophthalmic). Study the mechanism, listed uses and warnings from the US label on one sourced card.
Generic name
Ofloxacin
Class
Fluoroquinolone antibacterial (ophthalmic)
Mechanism
Quinolone antimicrobial active against susceptible gram-positive and gram-negative bacteria causing eye infections.
Used for
Bacterial conjunctivitis caused by listed susceptible organisms; safety and effectiveness below age 1 are not established; Bacterial corneal ulcers caused by listed susceptible organisms; safety and effectiveness below age 1 are not established
Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.
Label date: 20260814 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Interferes with bacterial DNA gyrase, an enzyme needed for bacterial DNA synthesis.
On both cards: Common side effects — Itching · Interactions — Theophylline (systemic quinolones); Warfarin (systemic quinolones)
Only on the Ciprofloxacin (ophthalmic) card: Used for — Corneal ulcers caused by the listed susceptible organisms; Bacterial conjunctivitis caused by the listed susceptible organisms · Common side effects — Local burning / discomfort; White crystalline precipitates; Lid margin crusting; Foreign body sensation · Warnings — Not for injection into the eye; Serious, occasionally fatal anaphylaxis has been reported with systemic quinolones; hypersensitivity history requires attention; Remove contact lenses before use · Interactions — Cyclosporine (systemic quinolones)
Mechanism: Fluoroquinolone that inhibits bacterial DNA gyrase, a topoisomerase needed for DNA replication, repair, and transcription.
On both cards: Warnings — Hypersensitivity to quinolones (contraindicated)
Only on the Ofloxacin (otic) card: Used for — Otitis externa from labeled susceptible bacteria in adults and children aged 6 months and older; Chronic suppurative otitis media from labeled susceptible bacteria with perforated tympanic membranes in patients aged 12 years and older; Acute otitis media from labeled susceptible bacteria in children aged 1 year and older with tympanostomy tubes · Common side effects — Application site reaction; Pruritus; Earache; Dizziness
Mechanism: Inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, disrupting processes required for bacterial DNA replication and maintenance.
Only on the Ciprofloxacin card: Used for — UTIs due to specified susceptible bacteria in adults, and selected complicated UTI/pyelonephritis in children aged 1–17; acute uncomplicated cystitis use is reserved for patients without alternatives; Specified susceptible lower-respiratory infections in adults; acute chronic-bronchitis exacerbation use is reserved for patients without alternatives; Specified susceptible skin, bone and joint infections in adults; Post-exposure inhalational anthrax and source-specified plague treatment/prevention in adults and children · Common side effects — Nausea; Diarrhea; Abnormal liver function tests; Vomiting; Rash · Warnings — QT prolongation; Hepatotoxicity; C. difficile-associated diarrhea · Interactions — Tizanidine (contraindicated); Theophylline; Other CYP1A2 substrates
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.
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