Esomeprazole magnesium — Proton pump inhibitor (PPI). Study the mechanism, listed uses and warnings from the US label on one sourced card.
Generic name
Esomeprazole magnesium
Class
Proton pump inhibitor (PPI)
Mechanism
Converted in the parietal cell to an active inhibitor that blocks the H+/K+ ATPase (proton pump), suppressing gastric acid secretion.
Used for
Short-term erosive-esophagitis healing in adults and ages 12–17; maintenance of healing in adults; Short-term heartburn and other GERD symptoms in adults and ages 12–17; Reduce NSAID-associated gastric-ulcer risk in adults receiving continuous NSAIDs who are aged 60 or older and/or have a documented gastric-ulcer history; With amoxicillin and clarithromycin, eradicate H. pylori in adults with active duodenal ulcer or a history within 5 years to reduce recurrence
C. difficile-associated diarrhea; Bone fracture with long-term use; Acute tubulointerstitial nephritis
Interactions
Clopidogrel; Some antiretrovirals (e.g., rilpivirine)
Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.
Label date: 20260825 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Substituted benzimidazole that inhibits the H+/K+ ATPase (proton pump) of the gastric parietal cell, blocking the final step of acid secretion.
On both cards: Common side effects — Headache; Diarrhea; Nausea; Flatulence; Abdominal pain · Warnings — C. difficile-associated diarrhea; Bone fracture with long-term use; Acute tubulointerstitial nephritis · Interactions — Clopidogrel
Only on the Omeprazole card: Used for — Short-term treatment of active duodenal or benign gastric ulcer in adults; H. pylori eradication with the specified antibiotics in adults with duodenal ulcer disease; Short-term symptomatic GERD or erosive esophagitis treatment, and maintenance of healed erosive esophagitis, in patients aged 2 years and older; Long-term treatment of pathological hypersecretory conditions in adults · Interactions — Rilpivirine, atazanavir, nelfinavir; Warfarin
Mechanism: Covalently binds the H+/K+ ATPase of the gastric parietal cell, suppressing the final step of acid production, basal and stimulated.
On both cards: Common side effects — Headache; Diarrhea; Nausea; Abdominal pain · Warnings — C. difficile-associated diarrhea; Bone fracture with long-term use
Only on the Pantoprazole card: Used for — Short-term healing and symptom relief of GERD-associated erosive esophagitis in adults and children aged 5 years and older; Maintenance of healed erosive esophagitis and reduction of heartburn relapse in adults with GERD; Long-term treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome, in adults · Warnings — Vitamin B12 deficiency · Interactions — Rilpivirine-containing antiretrovirals; Warfarin; Methotrexate
Mechanism: Binds GC-C on the intestinal lumen, raising cGMP; increases intestinal fluid secretion and transit.
On both cards: Common side effects — Diarrhea; Flatulence; Abdominal pain
Only on the Linaclotide card: Used for — IBS with constipation in adults and children aged 7 or older; Chronic idiopathic constipation in adults; Functional constipation in children aged 2 or older · Common side effects — Abdominal distension · Warnings — Severe diarrhea; Mechanical GI obstruction (contraindicated)
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.
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