Dorzolamide / Timolol: study card

Dorzolamide / Timolol — Carbonic anhydrase inhibitor + beta-blocker. Study the mechanism, listed uses and warnings from the US label on one sourced card.

Generic name
Dorzolamide / Timolol
Class
Carbonic anhydrase inhibitor + beta-blocker
Mechanism
Both reduce aqueous humor secretion: dorzolamide inhibits carbonic anhydrase II; timolol is a non-selective beta-blocker.
Used for
Elevated intraocular pressure in open-angle glaucoma or ocular hypertension when beta-blockers alone do not achieve the target IOP
Common side effects
Taste perversion; Ocular burning or stinging; Conjunctival hyperemia; Blurred vision; Eye itching
Warnings
Contraindicated with asthma or a history of asthma, or severe COPD; Contraindicated with sinus bradycardia, second/third-degree AV block, overt heart failure or cardiogenic shock; Sulfonamide hypersensitivity can occur despite topical administration
Interactions
Oral carbonic anhydrase inhibitors; Systemic beta-blockers; Calcium antagonists, digitalis

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

Drug class families: Beta-adrenergic blockers

Read the source label ↗

Label date: 20260813 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.

Pronunciation

Dorzolamide: dor-ZOLE-a-mide · Timolol: TYE-moe-lol

Pronunciation is shown for the US English generic name.

Other drugs in the same class

Beta-adrenergic blockers: Metoprolol, Carvedilol, Atenolol, Propranolol, Nebivolol, Timolol maleate (ophthalmic), Bisoprolol, Labetalol

Body system

Eye & ear · 19 Drug cards

Compare with related cards

Metoprolol

Same class family: Beta-adrenergic blockers

Mechanism: Beta-1 selective (cardioselective) adrenergic receptor blocker without intrinsic sympathomimetic activity; blocks beta-2 at higher levels.

Only on the Metoprolol card: Used for — Hypertension in adults; Long-term angina pectoris treatment to reduce attacks and improve exercise tolerance; Reduction of cardiovascular mortality in hemodynamically stable patients with definite or suspected acute myocardial infarction · Common side effects — Tiredness; Dizziness; Depression; Shortness of breath; Bradycardia · Warnings — Abrupt cessation may worsen ischemia; Worsening heart failure; May mask hypoglycemia · Interactions — Catecholamine-depleting drugs; CYP2D6 inhibitors; Digoxin, clonidine, diltiazem, verapamil

Carvedilol

Same class family: Beta-adrenergic blockers

Mechanism: Racemic mixture: nonselective beta-blockade from the S(-) enantiomer and alpha-1 blockade from both enantiomers; no intrinsic sympathomimetic activity.

Only on the Carvedilol card: Used for — Mild-to-severe chronic heart failure of ischemic or cardiomyopathic origin, usually with other heart-failure medicines; Reduction of cardiovascular mortality in clinically stable survivors of acute myocardial infarction with LVEF at or below 40%; Essential hypertension · Common side effects — Dizziness; Fatigue; Hypotension; Bradycardia; Hyperglycemia · Warnings — Do not abruptly discontinue; Bronchial asthma / bronchospastic conditions; May mask hypoglycemia · Interactions — CYP2D6 inhibitors, rifampin; Digoxin, cyclosporine; Clonidine, reserpine, MAO inhibitors

Atenolol

Same class family: Beta-adrenergic blockers

Mechanism: Beta-1 selective adrenergic blocker without membrane stabilizing or intrinsic sympathomimetic activity; selectivity lost at higher doses.

Only on the Atenolol card: Used for — Hypertension · Common side effects — Tiredness / fatigue; Dizziness; Cold extremities; Bradycardia; Depression · Warnings — Contraindicated in sinus bradycardia, >1st-degree block; Contraindicated in cardiogenic shock / overt failure · Interactions — Catecholamine depletors (reserpine); Calcium channel blockers, disopyramide, amiodarone; Clonidine withdrawal

An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.