Labetalol: study card

Labetalol — Alpha-1 + nonselective beta-blocker. Study the mechanism, listed uses and warnings from the US label on one sourced card.

Generic name
Labetalol
Class
Alpha-1 + nonselective beta-blocker
Mechanism
Combines selective competitive alpha1 blockade with nonselective competitive beta blockade.
Used for
Hypertension in adults
Common side effects
Fatigue; Nausea; Dizziness
Warnings
Postural hypotension / syncope; Bradycardia / heart block; Heart failure
Interactions
Digitalis glycosides and other drugs that slow heart rate; coadministration with non-dihydropyridine calcium-channel blockers such as verapamil is contraindicated; Beta-agonist bronchodilators: bronchodilation may be antagonized; Nitroglycerin: additive blood-pressure lowering

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

Drug class families: Beta-adrenergic blockers · Alpha-1 adrenergic blockers

Read the source label ↗

Label date: 20260325 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.

Pronunciation

Labetalol: la-BET-a-lol

Pronunciation is shown for the US English generic name.

Other drugs in the same class

Beta-adrenergic blockers: Dorzolamide / Timolol, Metoprolol, Atenolol, Propranolol

Alpha-1 adrenergic blockers: Tamsulosin, Carvedilol, Doxazosin, Terazosin

Body system

Cardiovascular · 47 Drug cards

Compare with related cards

Doxazosin

Same class family: Alpha-1 adrenergic blockers

Mechanism: Selectively blocks postjunctional alpha-1 receptors, lowering urethral resistance and systemic vascular resistance.

On both cards: Common side effects — Fatigue; Dizziness · Warnings — Postural hypotension / syncope

Only on the Doxazosin card: Used for — Benign prostatic hyperplasia (signs/symptoms); Hypertension · Common side effects — Malaise; Hypotension · Warnings — Intraoperative floppy iris syndrome; Screen for prostate cancer · Interactions — Strong CYP3A inhibitors; PDE-5 inhibitors

Metoprolol

Same class family: Beta-adrenergic blockers

Mechanism: Beta-1 selective (cardioselective) adrenergic receptor blocker without intrinsic sympathomimetic activity; blocks beta-2 at higher levels.

On both cards: Used for — Hypertension in adults · Common side effects — Dizziness

Only on the Metoprolol card: Used for — Long-term angina pectoris treatment to reduce attacks and improve exercise tolerance; Reduction of cardiovascular mortality in hemodynamically stable patients with definite or suspected acute myocardial infarction · Common side effects — Tiredness; Depression; Shortness of breath; Bradycardia · Warnings — Abrupt cessation may worsen ischemia; Worsening heart failure; May mask hypoglycemia · Interactions — Catecholamine-depleting drugs; CYP2D6 inhibitors; Digoxin, clonidine, diltiazem, verapamil

Carvedilol

Same class family: Beta-adrenergic blockers

Mechanism: Racemic mixture: nonselective beta-blockade from the S(-) enantiomer and alpha-1 blockade from both enantiomers; no intrinsic sympathomimetic activity.

On both cards: Common side effects — Fatigue; Dizziness

Only on the Carvedilol card: Used for — Mild-to-severe chronic heart failure of ischemic or cardiomyopathic origin, usually with other heart-failure medicines; Reduction of cardiovascular mortality in clinically stable survivors of acute myocardial infarction with LVEF at or below 40%; Essential hypertension · Common side effects — Hypotension; Bradycardia; Hyperglycemia · Warnings — Do not abruptly discontinue; Bronchial asthma / bronchospastic conditions; May mask hypoglycemia · Interactions — CYP2D6 inhibitors, rifampin; Digoxin, cyclosporine; Clonidine, reserpine, MAO inhibitors

An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.