Immunology
6 source-linked study cards in this body system.
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How each medicine works
Medicines in this body system: 6
| Prednisone — Synthetic adrenocortical steroid with potent anti-inflammatory effects; causes varied metabolic effects and modifies immune responses. |
| Hydroxychloroquine — 4-aminoquinoline antimalarial; anti-inflammatory and immunomodulatory mechanisms in RA and lupus are not fully known. |
| Methotrexate — Inhibits dihydrofolate reductase, interfering with tetrahydrofolate-dependent purine and thymidylate synthesis, DNA synthesis/repair and cellular replication. Its mechanism in rheumatoid arthritis and psoriasis is unknown. |
| Colchicine — May interfere with inflammasome assembly in neutrophils/monocytes (IL-1 beta activation) and inhibits beta-tubulin polymerization. |
| Prednisolone sodium phosphate — Synthetic adrenocortical steroid with predominantly glucocorticoid, anti-inflammatory and immunosuppressive effects. |
| Adalimumab — Binds TNF-alpha and blocks its interaction with p55 and p75 cell surface TNF receptors. |
Each summary is the mechanism line from the medicine’s study card.
Listed most often on cards in this body system
Used for
Rheumatoid arthritis in adults · 2/6: Hydroxychloroquine, Methotrexate
Common side effects
Fluid retention · 2/6: Prednisone, Prednisolone sodium phosphate
Altered glucose tolerance · 2/6: Prednisone, Prednisolone sodium phosphate
Elevated blood pressure · 2/6: Prednisone, Prednisolone sodium phosphate
Increased appetite, weight gain · 2/6: Prednisone, Prednisolone sodium phosphate
Boxed warning
2/6: Methotrexate, Adalimumab
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.