Prednisone: study card

Prednisone — Glucocorticoid (corticosteroid). Study the mechanism, listed uses and warnings from the US label on one sourced card.

Generic name
Prednisone
Class
Glucocorticoid (corticosteroid)
Mechanism
Synthetic adrenocortical steroid with potent anti-inflammatory effects; causes varied metabolic effects and modifies immune responses.
Used for
Specified severe allergic and dermatologic disorders under the label's condition-specific restrictions; Specified rheumatologic and respiratory disorders; Specified endocrine conditions; Palliation of specified neoplastic conditions
Common side effects
Fluid retention; Altered glucose tolerance; Elevated blood pressure; Mood changes; Increased appetite, weight gain
Warnings
HPA axis suppression, Cushing's syndrome; Immunosuppression, infection risk; Behavioral and mood disturbances
Interactions
Warfarin: response may change and coagulation monitoring is needed; CYP3A4 inducers and inhibitors; NSAIDs, including aspirin

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

Read the source label ↗

Label date: 20260923 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.

Pronunciation

Prednisone: PRED-ni-sone

Pronunciation is shown for the US English generic name.

Body system

Immunology · 6 Drug cards

Compare with related cards

Methylprednisolone

Same class on both cards

Mechanism: Synthetic glucocorticoid with potent anti-inflammatory effects; causes profound metabolic effects and modifies immune responses.

Only on the Methylprednisolone card: Used for — Selected endocrine disorders including adrenal insufficiency; hydrocortisone or cortisone is first choice and mineralocorticoid supplementation may be needed; Short-term adjunctive treatment of specified rheumatic disorders, and selected collagen-disease exacerbations or maintenance settings; Severe or incapacitating allergic conditions, including bronchial asthma, inadequately controlled by conventional treatment; Specified dermatologic conditions and severe allergic or inflammatory eye conditions · Common side effects — Fluid and sodium retention; Hypertension; Muscle weakness / osteoporosis; Cushingoid state; Impaired wound healing · Warnings — Systemic fungal infection and hypersensitivity are contraindications; Immunosuppression increases susceptibility to infection and may mask infection symptoms; Latent infections, including tuberculosis or hepatitis B, can reactivate · Interactions — Cyclosporine; Enzyme inducers (phenobarbital, phenytoin, rifampin); Ketoconazole

Dexamethasone

Same class on both cards

Mechanism: Synthetic glucocorticoid with potent anti-inflammatory effects and profound, varied metabolic effects.

Only on the Dexamethasone card: Used for — Selected endocrine disorders, including adrenal insufficiency, when oral therapy is not feasible and the injection/route is appropriate; hydrocortisone or cortisone is preferred for adrenal replacement; Short-term adjunctive treatment of specified rheumatic disorders; Specified severe allergic or inflammatory disorders under the label’s condition, route and preparation restrictions; severe allergic states must be unresponsive to adequate conventional treatment · Common side effects — Sodium and fluid retention; Potassium loss; Muscle weakness; Osteoporosis; Peptic ulcer · Warnings — Systemic fungal infections (contraindicated); Serious neurologic events with epidural injection

Prednisolone sodium phosphate

Same body system: Immunology

Mechanism: Synthetic adrenocortical steroid with predominantly glucocorticoid, anti-inflammatory and immunosuppressive effects.

On both cards: Common side effects — Fluid retention; Altered glucose tolerance; Elevated blood pressure; Increased appetite, weight gain

Only on the Prednisolone sodium phosphate card: Used for — Severe or incapacitating selected allergic conditions unresponsive to adequate conventional treatment; Selected rheumatologic and dermatologic conditions listed in the source, including condition-specific adjunctive or short-term regimens; Selected respiratory, gastrointestinal and hematologic conditions with the source’s condition-specific restrictions; Selected endocrine conditions; for adrenal insufficiency the source identifies hydrocortisone or cortisone as first choice · Common side effects — Mood / behavioral changes · Warnings — HPA axis suppression, Cushing's, hyperglycemia; Immunosuppression / infection risk; Bone density loss; cataracts, glaucoma · Interactions — Anticoagulants (warfarin); Amphotericin B / potassium-depleting agents; Anticholinesterase agents

An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.