Colchicine: study card

Generic name

Colchicine

Class

Alkaloid anti-inflammatory (microtubule inhibitor)

Mechanism

May interfere with inflammasome assembly in neutrophils/monocytes (IL-1 beta activation) and inhibits beta-tubulin polymerization.

Used for

Familial Mediterranean fever in adults and children aged 4 or older

Common side effects

Abdominal pain; Diarrhea; Nausea; Vomiting

Warnings

Fatal overdoses; keep from children; Blood dyscrasias (myelosuppression); Neuromuscular toxicity / rhabdomyolysis

Interactions

P-gp inhibitors; Strong CYP3A4 inhibitors (e.g., protease inhibitors)

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

Label date: 20260820 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.