Genitourinary

11 source-linked study cards in this body system.

Tamsulosin
Finasteride
Oxybutynin
Sildenafil
Tadalafil
Doxazosin
Mirabegron
Phenazopyridine
TerazosinTezruly
Dutasteride
Solifenacin

Drug classes in this body system

How each medicine works

Medicines in this body system: 11 · in a drug class: 7 · drug classes: 3

Tamsulosin — Blocks alpha-1 adrenoceptors with selectivity for receptors in the human prostate. Relaxation of prostate and bladder-neck smooth muscle improves urine flow and BPH symptoms.
Finasteride — Competitive, specific inhibitor of type II 5-alpha reductase, blocking conversion of testosterone to DHT.
Oxybutynin — Relaxes bladder smooth muscle by a direct antispasmodic effect and by inhibiting the muscarinic action of acetylcholine.
Sildenafil — During sexual stimulation, PDE5 inhibition enhances nitric oxide effects by reducing cGMP breakdown in the corpus cavernosum, supporting smooth-muscle relaxation and blood inflow. Recommended doses have no effect in the absence of sexual stimulation.
Tadalafil — Inhibits PDE5, raising cGMP in corpus cavernosum smooth muscle; needs sexual stimulation to release nitric oxide.
Doxazosin — Selectively blocks postjunctional alpha-1 receptors, lowering urethral resistance and systemic vascular resistance.
Mirabegron — Activates beta-3 receptors, relaxing the detrusor during bladder filling and increasing bladder capacity.
Phenazopyridine — Excreted in urine, where it exerts a topical analgesic effect on urinary tract mucosa; exact mechanism unknown.
Terazosin — Alpha-1 adrenoceptor antagonist; relaxes smooth muscle, easing the dynamic component of BPH outlet obstruction.
Dutasteride — Competitively inhibits type 1 and type 2 5-alpha reductase, blocking conversion of testosterone to DHT.
Solifenacin — Competitive muscarinic receptor antagonist; muscarinic receptors mediate cholinergic bladder smooth muscle contraction.

Each summary is the mechanism line from the medicine’s study card.

Listed most often on cards in this body system

Common side effects

Headache · 6/11: Tamsulosin, Oxybutynin, Sildenafil, Tadalafil, Mirabegron, Phenazopyridine

An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.