Antimuscarinic bladder medicines
Compare the named medicines in this source-linked class directory.
Membership describes a named action or a component of a combination. A medicine may appear in several families. Medicines in one family are not automatically interchangeable; this is a study directory, not a prescribing guide.
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Generic names and pronunciation
| Oxybutynin · ox-i-BYOO-ti-nin |
| Solifenacin · sol-i-FEN-a-sin |
Pronunciation is shown for the US English generic name.
Body system and related classes
Body system: Genitourinary
How each medicine works
| Oxybutynin — Relaxes bladder smooth muscle by a direct antispasmodic effect and by inhibiting the muscarinic action of acetylcholine. |
| Solifenacin — Competitive muscarinic receptor antagonist; muscarinic receptors mediate cholinergic bladder smooth muscle contraction. |
Each summary is the mechanism line from the medicine’s study card.
What each medicine is used for
| Oxybutynin — Overactive bladder with urge urinary incontinence, urgency and frequency; Symptoms of detrusor overactivity associated with a neurological condition in children aged 6 or older |
| Solifenacin — Overactive bladder with urgency, urinary frequency or urge urinary incontinence in adults |
Each list is the uses line from the medicine’s study card.
Telling these medicines apart
Medicines in this class: 2
Listed on more than one card in this class
Common side effects
Dry mouth · 2/2: Oxybutynin, Solifenacin
Constipation · 2/2: Oxybutynin, Solifenacin
Listed on only one card in this class
Oxybutynin: Common side effects — Diarrhea; Headache; Somnolence · Warnings — Urinary retention, gastric retention or severe decreased gastrointestinal motility; uncontrolled narrow-angle glaucoma are contraindications; Angioedema; Anticholinergic CNS effects · Interactions — Other anticholinergic drugs; Prokinetic agents (metoclopramide)
Solifenacin: Common side effects — Urinary tract infection; Blurred vision · Warnings — Angioedema and anaphylaxis; Urinary retention (outlet obstruction); QT prolongation in high-risk patients · Interactions — Strong CYP3A4 inhibitors (e.g., ketoconazole)
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.