Doxazosin: study card

Doxazosin — Alpha-1 adrenergic antagonist. Study the mechanism, listed uses and warnings from the US label on one sourced card.

Generic name
Doxazosin
Class
Alpha-1 adrenergic antagonist
Mechanism
Selectively blocks postjunctional alpha-1 receptors, lowering urethral resistance and systemic vascular resistance.
Used for
Benign prostatic hyperplasia (signs/symptoms); Hypertension
Common side effects
Fatigue; Malaise; Hypotension; Dizziness
Warnings
Postural hypotension / syncope; Intraoperative floppy iris syndrome; Screen for prostate cancer
Interactions
Strong CYP3A inhibitors; PDE-5 inhibitors

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

Drug class families: Alpha-1 adrenergic blockers

Read the source label ↗

Label date: 20260708 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.

Pronunciation

Doxazosin: dox-AY-zoe-sin

Pronunciation is shown for the US English generic name.

Other drugs in the same class

Alpha-1 adrenergic blockers: Terazosin, Labetalol, Tamsulosin, Carvedilol

Body system

Genitourinary · 11 Drug cards

Compare with related cards

Carvedilol

Same class family: Alpha-1 adrenergic blockers

Mechanism: Racemic mixture: nonselective beta-blockade from the S(-) enantiomer and alpha-1 blockade from both enantiomers; no intrinsic sympathomimetic activity.

On both cards: Common side effects — Fatigue; Hypotension; Dizziness

Only on the Carvedilol card: Used for — Mild-to-severe chronic heart failure of ischemic or cardiomyopathic origin, usually with other heart-failure medicines; Reduction of cardiovascular mortality in clinically stable survivors of acute myocardial infarction with LVEF at or below 40%; Essential hypertension · Common side effects — Bradycardia; Hyperglycemia · Warnings — Do not abruptly discontinue; Bronchial asthma / bronchospastic conditions; May mask hypoglycemia · Interactions — CYP2D6 inhibitors, rifampin; Digoxin, cyclosporine; Clonidine, reserpine, MAO inhibitors

Labetalol

Same class family: Alpha-1 adrenergic blockers

Mechanism: Combines selective competitive alpha1 blockade with nonselective competitive beta blockade.

On both cards: Common side effects — Fatigue; Dizziness · Warnings — Postural hypotension / syncope

Only on the Labetalol card: Used for — Hypertension in adults · Common side effects — Nausea · Warnings — Bradycardia / heart block; Heart failure · Interactions — Digitalis glycosides and other drugs that slow heart rate; coadministration with non-dihydropyridine calcium-channel blockers such as verapamil is contraindicated; Beta-agonist bronchodilators: bronchodilation may be antagonized; Nitroglycerin: additive blood-pressure lowering

Tamsulosin

Same class family: Alpha-1 adrenergic blockers

Mechanism: Blocks alpha-1 adrenoceptors with selectivity for receptors in the human prostate. Relaxation of prostate and bladder-neck smooth muscle improves urine flow and BPH symptoms.

On both cards: Common side effects — Dizziness · Warnings — Intraoperative floppy iris syndrome

Only on the Tamsulosin card: Used for — Benign prostatic hyperplasia (signs and symptoms) · Common side effects — Headache; Rhinitis; Abnormal ejaculation; Asthenia · Warnings — Orthostatic hypotension, syncope; Priapism · Interactions — Strong CYP3A4 inhibitors, such as ketoconazole; PDE5 inhibitors: possible symptomatic hypotension; Warfarin: caution is advised because interaction studies are inconclusive

An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.