Valacyclovir: study card

Valacyclovir — Nucleoside analogue DNA polymerase inhibitor (antiviral). Study the mechanism, listed uses and warnings from the US label on one sourced card.

Generic name
Valacyclovir
Class
Nucleoside analogue DNA polymerase inhibitor (antiviral)
Mechanism
Deoxynucleoside analogue DNA polymerase inhibitor; antiviral active against alpha-herpes viruses.
Used for
Cold sores in adults and children aged 12 or older; Genital-herpes treatment and suppression in the adult populations specified by the label; Herpes zoster in immunocompetent adults; Chickenpox in immunocompetent children aged 2 to under 18
Common side effects
Headache; Nausea; Abdominal pain
Warnings
TTP / HUS; Acute renal failure; CNS reactions (agitation, confusion)

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

Read the source label ↗

Label date: 20260905 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.

Pronunciation

Valacyclovir: val-ay-SYE-kloe-veer

Pronunciation is shown for the US English generic name.

Body system

Infectious disease · 21 Drug cards

Compare with related cards

Cefdinir

Same body system: Infectious disease

Mechanism: Cephalosporin (beta-lactam) antibacterial; inhibits bacterial cell wall synthesis.

On both cards: Common side effects — Headache; Nausea; Abdominal pain

Only on the Cefdinir card: Used for — Mild-to-moderate community-acquired pneumonia due to specified susceptible bacteria in adults and adolescents; Acute exacerbations of chronic bronchitis due to specified susceptible bacteria in adults and adolescents; Acute maxillary sinusitis due to specified susceptible bacteria; pediatric use is addressed in the source-specific dosing section; Streptococcus pyogenes pharyngitis or tonsillitis in the adult/adolescent and pediatric populations specified by the label · Common side effects — Diarrhea; Vaginal moniliasis · Warnings — Cephalosporin hypersensitivity is a contraindication; serious cross-allergic reactions can occur; C. difficile-associated diarrhea may progress to severe or fatal colitis

Fluconazole

Same body system: Infectious disease

Mechanism: Selectively inhibits fungal CYP450 lanosterol 14-alpha-demethylase, blocking ergosterol synthesis (fungistatic).

On both cards: Common side effects — Headache; Nausea; Abdominal pain

Only on the Fluconazole card: Used for — Vaginal candidiasis; Oropharyngeal and esophageal candidiasis; Cryptococcal meningitis; Reduction of candidiasis in bone-marrow transplant patients receiving cytotoxic chemotherapy and/or radiation therapy · Common side effects — Diarrhea; Dyspepsia · Warnings — Hypersensitivity; caution with other azole allergy; Contraindicated with QT-prolonging CYP3A4 substrates; Rare serious liver injury, including fatal cases, and severe exfoliative skin reactions have been reported; Pregnancy exposure requires risk review: high-dose first-trimester exposure has been associated with a distinct birth-defect pattern; lower-dose observational signals have important limitations

Azithromycin

Same body system: Infectious disease

Mechanism: Binds to the bacterial 50S ribosomal subunit and interrupts protein synthesis.

On both cards: Common side effects — Nausea; Abdominal pain

Only on the Azithromycin card: Used for — Community-acquired pneumonia caused by the specified susceptible bacteria in adults or children aged 6 months and older who are appropriate for oral treatment; Streptococcal pharyngitis or tonsillitis in adults or children aged 2 years and older who cannot use first-line therapy; Acute otitis media caused by the specified susceptible bacteria in children aged 6 months and older; Urethritis or cervicitis caused by the specified susceptible organisms in adults · Common side effects — Diarrhea; Vomiting · Warnings — Serious allergic and skin reactions; Hepatotoxicity; QT prolongation / torsades de pointes

An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.