Fluconazole: study card

Fluconazole — Triazole antifungal. Study the mechanism, listed uses and warnings from the US label on one sourced card.

Generic name
Fluconazole
Class
Triazole antifungal
Mechanism
Selectively inhibits fungal CYP450 lanosterol 14-alpha-demethylase, blocking ergosterol synthesis (fungistatic).
Used for
Vaginal candidiasis; Oropharyngeal and esophageal candidiasis; Cryptococcal meningitis; Reduction of candidiasis in bone-marrow transplant patients receiving cytotoxic chemotherapy and/or radiation therapy
Common side effects
Headache; Nausea; Abdominal pain; Diarrhea; Dyspepsia
Warnings
Hypersensitivity; caution with other azole allergy; Contraindicated with QT-prolonging CYP3A4 substrates; Rare serious liver injury, including fatal cases, and severe exfoliative skin reactions have been reported; Pregnancy exposure requires risk review: high-dose first-trimester exposure has been associated with a distinct birth-defect pattern; lower-dose observational signals have important limitations
Interactions
Erythromycin; Pimozide; Quinidine

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

Read the source label ↗

Label date: 20260622 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.

Pronunciation

Fluconazole: floo-KOE-na-zole

Pronunciation is shown for the US English generic name.

Body system

Infectious disease · 21 Drug cards

Compare with related cards

Cephalexin

Same body system: Infectious disease

Mechanism: Disrupts bacterial cell-wall synthesis, producing a bactericidal effect against susceptible organisms.

On both cards: Common side effects — Nausea; Abdominal pain; Diarrhea; Dyspepsia

Only on the Cephalexin card: Used for — Respiratory infections caused by the specified susceptible bacteria; Otitis media caused by the specified susceptible bacteria; Skin and skin-structure infections caused by the specified susceptible bacteria; Bone or genitourinary infections caused by the specified susceptible bacteria · Common side effects — Vomiting · Warnings — Serious hypersensitivity (anaphylactic) reactions; C. difficile-associated diarrhea; Seizure potential · Interactions — Metformin; Probenecid

Cefdinir

Same body system: Infectious disease

Mechanism: Cephalosporin (beta-lactam) antibacterial; inhibits bacterial cell wall synthesis.

On both cards: Common side effects — Headache; Nausea; Abdominal pain; Diarrhea

Only on the Cefdinir card: Used for — Mild-to-moderate community-acquired pneumonia due to specified susceptible bacteria in adults and adolescents; Acute exacerbations of chronic bronchitis due to specified susceptible bacteria in adults and adolescents; Acute maxillary sinusitis due to specified susceptible bacteria; pediatric use is addressed in the source-specific dosing section; Streptococcus pyogenes pharyngitis or tonsillitis in the adult/adolescent and pediatric populations specified by the label · Common side effects — Vaginal moniliasis · Warnings — Cephalosporin hypersensitivity is a contraindication; serious cross-allergic reactions can occur; C. difficile-associated diarrhea may progress to severe or fatal colitis · Interactions — Aluminum / magnesium antacids; Iron supplements; Probenecid

Azithromycin

Same body system: Infectious disease

Mechanism: Binds to the bacterial 50S ribosomal subunit and interrupts protein synthesis.

On both cards: Common side effects — Nausea; Abdominal pain; Diarrhea

Only on the Azithromycin card: Used for — Community-acquired pneumonia caused by the specified susceptible bacteria in adults or children aged 6 months and older who are appropriate for oral treatment; Streptococcal pharyngitis or tonsillitis in adults or children aged 2 years and older who cannot use first-line therapy; Acute otitis media caused by the specified susceptible bacteria in children aged 6 months and older; Urethritis or cervicitis caused by the specified susceptible organisms in adults · Common side effects — Vomiting · Warnings — Serious allergic and skin reactions; Hepatotoxicity; QT prolongation / torsades de pointes · Interactions — Nelfinavir; Warfarin

An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.