Polymyxin B / Trimethoprim (ophthalmic): study card

Polymyxin B / Trimethoprim (ophthalmic) — Ophthalmic antibacterial combination. Study the mechanism, listed uses and warnings from the US label on one sourced card.

Generic name: Polymyxin B / Trimethoprim (ophthalmic)
Class: Ophthalmic antibacterial combination
Mechanism: Trimethoprim reversibly inhibits bacterial dihydrofolate reductase, blocking tetrahydrofolic acid production.
Used for: Surface ocular bacterial infections, including acute bacterial conjunctivitis or blepharoconjunctivitis, due to listed susceptible organisms; safety and effectiveness below age 2 months are not established
Common side effects: Local irritation; Redness; Burning / stinging; Itching
Warnings: Hypersensitivity (lid edema, tearing, rash)

Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.

Read the source label ↗

Label date: 20260909 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.

Practice

Pronunciation

Polymyxin B: pol-ee-MIX-in BEE · Trimethoprim (ophthalmic): trye-METH-oh-prim

Pronunciation is shown for the US English generic name.

Body system

Eye & ear · 19 Drug cards

Compare with related cards

Ofloxacin (ophthalmic)

Same body system: Eye & ear

Mechanism: Quinolone antimicrobial active against susceptible gram-positive and gram-negative bacteria causing eye infections.

On both cards: Common side effects — Redness; Itching

Only on the Ofloxacin (ophthalmic) card: Used for — Bacterial conjunctivitis caused by listed susceptible organisms; safety and effectiveness below age 1 are not established; Bacterial corneal ulcers caused by listed susceptible organisms; safety and effectiveness below age 1 are not established · Common side effects — Transient ocular burning / discomfort; Stinging; Photophobia · Warnings — Hypersensitivity to quinolones (contraindicated)

An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.