Mesalamine — Aminosalicylate (5-ASA). Study the mechanism, listed uses and warnings from the US label on one sourced card.
Generic name
Mesalamine
Brands
Apriso
Class
Aminosalicylate (5-ASA)
Mechanism
5-ASA has an incompletely understood mechanism that appears to involve local anti-inflammatory effects on colonic epithelium; inhibition of prostanoid and leukotriene production is a possible mechanism.
Used for
Maintenance of ulcerative-colitis remission in adults, for the cited extended-release capsules
Label date: 20260827 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Substituted benzimidazole that inhibits the H+/K+ ATPase (proton pump) of the gastric parietal cell, blocking the final step of acid secretion.
On both cards: Common side effects — Headache; Diarrhea; Nausea
Only on the Omeprazole card: Used for — Short-term treatment of active duodenal or benign gastric ulcer in adults; H. pylori eradication with the specified antibiotics in adults with duodenal ulcer disease; Short-term symptomatic GERD or erosive esophagitis treatment, and maintenance of healed erosive esophagitis, in patients aged 2 years and older; Long-term treatment of pathological hypersecretory conditions in adults · Common side effects — Abdominal pain; Flatulence · Warnings — Acute tubulointerstitial nephritis; C. difficile-associated diarrhea; Bone fracture with long-term use · Interactions — Clopidogrel; Rilpivirine, atazanavir, nelfinavir; Warfarin
Mechanism: Covalently binds the H+/K+ ATPase of the gastric parietal cell, suppressing the final step of acid production, basal and stimulated.
On both cards: Common side effects — Headache; Diarrhea; Nausea
Only on the Pantoprazole card: Used for — Short-term healing and symptom relief of GERD-associated erosive esophagitis in adults and children aged 5 years and older; Maintenance of healed erosive esophagitis and reduction of heartburn relapse in adults with GERD; Long-term treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome, in adults · Common side effects — Abdominal pain · Warnings — C. difficile-associated diarrhea; Bone fracture with long-term use; Vitamin B12 deficiency · Interactions — Rilpivirine-containing antiretrovirals; Warfarin; Methotrexate
Mechanism: Converted in the parietal cell to an active inhibitor that blocks the H+/K+ ATPase (proton pump), suppressing gastric acid secretion.
On both cards: Common side effects — Headache; Diarrhea; Nausea
Only on the Esomeprazole magnesium card: Used for — Short-term erosive-esophagitis healing in adults and ages 12–17; maintenance of healing in adults; Short-term heartburn and other GERD symptoms in adults and ages 12–17; Reduce NSAID-associated gastric-ulcer risk in adults receiving continuous NSAIDs who are aged 60 or older and/or have a documented gastric-ulcer history; With amoxicillin and clarithromycin, eradicate H. pylori in adults with active duodenal ulcer or a history within 5 years to reduce recurrence · Common side effects — Flatulence; Abdominal pain · Warnings — C. difficile-associated diarrhea; Bone fracture with long-term use; Acute tubulointerstitial nephritis · Interactions — Clopidogrel; Some antiretrovirals (e.g., rilpivirine)
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.
Capsera