Loperamide — Antidiarrheal (gut opiate-receptor agonist). Study the mechanism, listed uses and warnings from the US label on one sourced card.
Generic name
Loperamide
Class
Antidiarrheal (gut opiate-receptor agonist)
Mechanism
Binds gut-wall opiate receptors, inhibiting acetylcholine and prostaglandin release; slows peristalsis and lengthens transit.
Used for
Symptomatic control of acute nonspecific diarrhea in patients aged 2 years and older; Symptomatic control of chronic diarrhea associated with inflammatory bowel disease in adults; Reduction of ileostomy discharge volume
Common side effects
Constipation; Dizziness
Boxed warning
Torsades de pointes, cardiac arrest, and death have been reported with higher than recommended dosages.
Warnings
Contraindicated below age 2; Contraindicated with acute dysentery or enterocolitis caused by invasive bacteria such as Salmonella, Shigella or Campylobacter; Contraindicated with abdominal pain without diarrhea
Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.
Label date: 20260728 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Competitive inhibitor of histamine-2 receptors; suppresses both acid concentration and volume of gastric secretion.
On both cards: Common side effects — Constipation; Dizziness
Only on the Famotidine card: Used for — Active duodenal or gastric ulcer, nonerosive GERD, or erosive esophagitis in adults and children weighing at least 40 kg; Pathological acid-hypersecretory conditions in adults; Reduction of duodenal-ulcer recurrence risk in adults · Common side effects — Headache; Diarrhea · Warnings — CNS adverse reactions (elderly, renal impairment); GI malignancy may be masked · Interactions — Medicines requiring gastric acidity for absorption; Tizanidine: potential increased exposure and hypotension, bradycardia or drowsiness; the source notes that this interaction has not been studied clinically
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.