Linagliptin: brand names and study card

Linagliptin — DPP-4 inhibitor. Study the mechanism, listed uses and warnings from the US label on one sourced card.

Generic name: Linagliptin
Brands: Tradjenta
Class: DPP-4 inhibitor
Mechanism: Inhibits DPP-4, raising active GLP-1 and GIP; increases glucose-dependent insulin release and lowers glucagon.
Used for: Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes
Common side effects: Nasopharyngitis; Hypoglycemia with insulin or secretagogues
Warnings: Pancreatitis; Severe, disabling arthralgia; Bullous pemphigoid
Interactions: Strong P-gp/CYP3A4 inducers (e.g., rifampin); Insulin and insulin secretagogues

Label date: 20250827 · For learning, not clinical decisions. US label and brand information; always consult the current source.

Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.

Practice

Pronunciation

Linagliptin: lin-a-GLIP-tin

Shared name ending: -gliptin · Sitagliptin

Pronunciation is shown for the US English generic name. A name ending is a memory cue, not a classification rule.

Other drugs in the same class

DPP-4 inhibitors: Sitagliptin

Body system

Endocrine · 27 Drug cards

Compare with related cards

Sitagliptin

Same class family: DPP-4 inhibitors

Mechanism: A DPP-4 inhibitor believed to act by slowing incretin inactivation. It increases and prolongs active GLP-1 and GIP levels, which influence insulin and glucagon in a glucose-dependent manner.

On both cards: Common side effects — Nasopharyngitis · Warnings — Pancreatitis

Only on the Sitagliptin card: Used for — Adjunct to diet and exercise for glycemic control in adults with type 2 diabetes · Common side effects — Upper respiratory tract infection; Headache · Warnings — Heart failure; Acute renal failure · Interactions — Insulin or insulin secretagogues (sulfonylureas)

An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.