MAO inhibitors; Cimetidine; Alcohol / CNS depressants
Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.
Label date: 20260904 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Mechanism is unknown. Preclinical studies show high 5-HT1A receptor affinity; buspirone also has moderate D2 affinity, no significant benzodiazepine-receptor affinity and no effect on GABA binding in the tested preclinical models.
On both cards: Common side effects — Nausea · Interactions — MAO inhibitors
Only on the Buspirone card: Used for — Anxiety disorders; Short-term relief of anxiety symptoms · Common side effects — Dizziness; Headache; Nervousness; Lightheadedness · Warnings — Contraindicated with MAOIs (serotonin syndrome); Hypersensitivity to buspirone · Interactions — Linezolid / IV methylene blue; CYP3A4 inhibitors and inducers
Mechanism: Thought to potentiate serotonin and norepinephrine in the CNS by inhibiting their reuptake.
On both cards: Common side effects — Nausea · Interactions — MAO inhibitors
Only on the Venlafaxine card: Used for — Major depressive disorder in adults; Generalized anxiety disorder in adults; Social anxiety disorder in adults; Panic disorder in adults · Common side effects — Somnolence; Dry mouth; Sweating; Abnormal ejaculation · Warnings — Serotonin syndrome; Elevated blood pressure; Discontinuation syndrome · Interactions — Other serotonergic drugs; Antiplatelets / anticoagulants
Mechanism: Binds the benzodiazepine site of GABA-A receptors in the brain, enhancing GABA-mediated synaptic inhibition.
On both cards: Warnings — CNS depression · Interactions — Alcohol / CNS depressants
Only on the Lorazepam card: Used for — Anxiety disorders in adults already receiving stable, evenly divided three-times-daily lorazepam tablets, when converted to the selected LOREEV XR formulation · Common side effects — Sedation; Dizziness; Weakness; Unsteadiness · Warnings — Contraindicated in acute narrow-angle glaucoma; Neonatal sedation and withdrawal · Interactions — Opioids; UGT inhibitors
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.