Baclofen — Muscle relaxant and antispastic agent. Study the mechanism, listed uses and warnings from the US label on one sourced card.
Generic name
Baclofen
Class
Muscle relaxant and antispastic agent
Mechanism
The precise mechanism is not fully known. Baclofen can inhibit monosynaptic and polysynaptic spinal reflexes, possibly by hyperpolarizing afferent terminals; supraspinal actions may also contribute.
Used for
Alleviation of reversible spasticity due to multiple sclerosis; May also be of value for patients with spinal cord injuries or other spinal cord diseases
Common side effects
Drowsiness; Dizziness; Weakness; Fatigue
Warnings
Abrupt withdrawal: hallucinations, seizures; Neonatal withdrawal if used in pregnancy; Not for rheumatic muscle spasm
Interactions
CNS depressants and alcohol
Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.
Label date: 20260903 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Relieves skeletal muscle spasm of local origin without interfering with muscle function. Animal studies support a mainly central action rather than a direct action at skeletal muscle or the neuromuscular junction.
On both cards: Common side effects — Dizziness; Fatigue
Only on the Cyclobenzaprine card: Used for — Short-term relief of muscle spasm from acute, painful musculoskeletal conditions, as an adjunct to rest and physical therapy · Common side effects — Dry mouth; Constipation; Somnolence · Warnings — Serotonin syndrome; TCA-like cardiovascular / CNS effects; Not recommended in elderly or hepatic impairment; The selected extended-release capsule is intended only for short periods, up to 2–3 weeks; effectiveness for central spasticity has not been established · Interactions — MAO inhibitors; Alcohol, barbiturates, CNS depressants; Tramadol
Mechanism: Not established; may be due to general CNS depression. No direct action on striated muscle, motor end plate or nerve fiber.
On both cards: Common side effects — Drowsiness · Interactions — CNS depressants and alcohol
Only on the Methocarbamol card: Used for — Adjunct to rest, physical therapy and other measures for discomfort associated with acute painful musculoskeletal conditions · Common side effects — Dizziness / lightheadedness; Nausea / vomiting; Headache; Blurred vision · Warnings — Hypersensitivity to methocarbamol; Alcohol and other CNS depressants can add to sedating effects; Mental or physical ability for driving and hazardous tasks may be impaired; Pregnancy use requires a clinician's benefit-risk assessment · Interactions — Pyridostigmine (myasthenia gravis)
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.
Capsera