Insulins
Compare the named medicines in this source-linked class directory.
Membership describes a named action or a component of a combination. A medicine may appear in several families. Medicines in one family are not automatically interchangeable; this is a study directory, not a prescribing guide.
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Combination: membership refers to the relevant component.
Generic names and pronunciation
| Insulin glargine · IN-su-lin GLAR-jeen |
| Insulin Lispro · IN-su-lin LYE-sproe |
| Insulin Aspart · IN-su-lin AS-part |
| Insulin degludec · IN-su-lin DEG-loo-dek |
| Insulin detemir · IN-su-lin DE-te-mir |
| Insulin Isophane · IN-su-lin EYE-soe-fane |
| Insulin Regular (human) · IN-su-lin REG-yoo-lar |
Pronunciation is shown for the US English generic name.
Body system and related classes
Body system: Endocrine
How each medicine works
| Insulin glargine — Regulates glucose metabolism: stimulates peripheral glucose uptake (muscle, fat) and inhibits hepatic glucose production. |
| Insulin Lispro — Lowers blood glucose by stimulating peripheral glucose uptake in muscle and fat and inhibiting hepatic glucose production. |
| Insulin Aspart — Regulates glucose metabolism: stimulates peripheral glucose uptake in muscle and fat and inhibits hepatic glucose production. |
| Insulin degludec — Lowers glucose by stimulating peripheral uptake and inhibiting hepatic output; forms multi-hexamers in subcutaneous tissue. |
| Insulin detemir — Regulates glucose metabolism: stimulates peripheral glucose uptake and inhibits hepatic glucose production, lipolysis, proteolysis. |
| Insulin Isophane / Insulin Regular (human) — Stimulates glucose uptake in skeletal muscle and fat and inhibits hepatic glucose production; pairs intermediate-acting insulin with faster-onset regular insulin. |
Each summary is the mechanism line from the medicine’s study card.
What each medicine is used for
| Insulin glargine — Glycemic control in adults and children aged 6 years and older with type 1 diabetes mellitus; Glycemic control in adults with type 2 diabetes mellitus |
| Insulin Lispro — Glycemic control in adults and pediatric patients with diabetes mellitus |
| Insulin Aspart — Glycemic control in adults and pediatric patients with diabetes mellitus |
| Insulin degludec — Glycemic control in diabetes mellitus from age 1 year |
| Insulin detemir — Glycemic control in adults and pediatric patients with diabetes mellitus |
| Insulin Isophane / Insulin Regular (human) — Diabetes mellitus in adults (glycemic control) |
Each list is the uses line from the medicine’s study card.
Telling these medicines apart
Medicines in this class: 6 · single-ingredient: 5 · combination products: 1
Listed on more than one card in this class
Used for
Glycemic control in adults and pediatric patients with diabetes mellitus · 3/6: Insulin Lispro, Insulin Aspart, Insulin detemir
Common side effects
Hypoglycemia · 6/6: Insulin glargine, Insulin Lispro, Insulin Aspart, Insulin degludec, Insulin detemir, Insulin Isophane / Insulin Regular (human)
Lipodystrophy · 6/6: Insulin glargine, Insulin Lispro, Insulin Aspart, Insulin degludec, Insulin detemir, Insulin Isophane / Insulin Regular (human)
Injection site reactions · 5/6: Insulin Lispro, Insulin Aspart, Insulin degludec, Insulin detemir, Insulin Isophane / Insulin Regular (human)
Allergic reactions · 4/6: Insulin Lispro, Insulin Aspart, Insulin degludec, Insulin detemir
Weight gain · 3/6: Insulin glargine, Insulin degludec, Insulin Isophane / Insulin Regular (human)
Edema · 2/6: Insulin glargine, Insulin Isophane / Insulin Regular (human)
Rash · 2/6: Insulin Lispro, Insulin Aspart
Warnings
Hypokalemia · 6/6: Insulin glargine, Insulin Lispro, Insulin Aspart, Insulin degludec, Insulin detemir, Insulin Isophane / Insulin Regular (human)
Hypoglycemia · 3/6: Insulin glargine, Insulin Lispro, Insulin Aspart
Hypoglycemia, may be life-threatening · 3/6: Insulin degludec, Insulin detemir, Insulin Isophane / Insulin Regular (human)
Never share pens or syringes · 2/6: Insulin Lispro, Insulin Isophane / Insulin Regular (human)
Never share pens or needles · 2/6: Insulin degludec, Insulin detemir
Interactions
Antidiabetic agents, ACE inhibitors, ARBs · 4/6: Insulin glargine, Insulin Lispro, Insulin Aspart, Insulin Isophane / Insulin Regular (human)
Fibrates, fluoxetine, MAOIs · 2/6: Insulin Lispro, Insulin Aspart
Other antidiabetic agents · 2/6: Insulin degludec, Insulin detemir
ACE inhibitors / ARBs · 2/6: Insulin degludec, Insulin detemir
Fluoxetine, MAOIs, salicylates · 2/6: Insulin degludec, Insulin detemir
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.