Spironolactone — Aldosterone antagonist (potassium-sparing diuretic). Study the mechanism, listed uses and warnings from the US label on one sourced card.
Competitively blocks aldosterone receptors in the distal tubule: more sodium and water excreted, potassium retained.
Used for
Heart failure with reduced ejection fraction, NYHA class III–IV; Add-on treatment for hypertension inadequately controlled by other agents; Edema in adults with cirrhosis or nephrotic syndrome when the specified underlying-disease, fluid/sodium and other-diuretic measures are insufficient; Primary hyperaldosteronism: short-term before surgery or long-term in the selected nonsurgical/adrenal-hyperplasia settings
Brand questions use only name pairings verified against the linked product source. Unverified pairings are withheld from these questions; the other study content remains available.
Label date: 20260909 · For learning, not clinical decisions. US label and brand information; always consult the current source.
Source snapshot checked: 2026-10-21. The source document and selected fields were compared. The complete card has not had an independent clinical review.
Mechanism: Inhibits angiotensin-converting enzyme, blocking conversion of angiotensin I to angiotensin II and suppressing the renin-angiotensin-aldosterone system.
On both cards: Common side effects — Dizziness; Headache · Warnings — Hyperkalemia · Interactions — Lithium; NSAIDs
Only on the Lisinopril card: Used for — Hypertension in adults and children aged 6 years and older; Adjunctive therapy for heart failure; Reduction of mortality after acute myocardial infarction in hemodynamically stable patients treated within 24 hours · Common side effects — Cough; Hypotension; Chest pain · Warnings — Angioedema; Renal impairment · Interactions — Diuretics
Mechanism: Selectively blocks angiotensin II binding to AT1 receptors, inhibiting its vasoconstrictor and aldosterone-secreting effects.
On both cards: Common side effects — Hyperkalemia; Dizziness; Headache · Interactions — Lithium; NSAIDs
Only on the Valsartan card: Used for — Hypertension in adults and children aged 6 years and older; Reduction of heart-failure hospitalization in adults with NYHA class II–IV heart failure; Reduction of cardiovascular mortality in clinically stable adults with left ventricular failure or dysfunction after myocardial infarction · Common side effects — Fatigue; Hypotension · Warnings — Hypotension; Renal function and potassium changes; No aliskiren in diabetes · Interactions — Potassium-sparing diuretics / supplements
Mechanism: Benazeprilat inhibits ACE, blocking conversion of angiotensin I to angiotensin II and lowering aldosterone.
On both cards: Common side effects — Dizziness; Headache · Warnings — Hyperkalemia · Interactions — Lithium; NSAIDs
Only on the Benazepril card: Used for — Hypertension in adults and children aged 6 years and older; pediatric use is not established with GFR below 30 mL/min/1.73 m² · Common side effects — Somnolence; Postural dizziness; Cough · Warnings — Angioedema; Renal impairment · Interactions — Neprilysin inhibitors (sacubitril)
An item counts as shared only when both cards use the same wording. If a card does not list an item, that is not a statement that the effect never occurs.
Capsera